Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1955756..1955899 Replicon chromosome
Accession NZ_CP117693
Organism Salmonella enterica subsp. enterica serovar London strain S1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1955795..1955897 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1955756..1955899 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTQ18_RS09310 1952180..1952878 - 699 WP_023255939.1 exodeoxyribonuclease X -
PTQ18_RS09315 1952902..1953558 - 657 WP_023245437.1 carbon-nitrogen hydrolase family protein -
PTQ18_RS09320 1953666..1953896 - 231 WP_000856224.1 DNA polymerase III subunit theta -
PTQ18_RS09325 1954034..1954408 + 375 WP_000168393.1 CopC domain-containing protein YobA -
PTQ18_RS09330 1954409..1955284 + 876 WP_000979694.1 copper homeostasis membrane protein CopD -
PTQ18_RS09335 1955301..1955654 + 354 WP_000722368.1 YebY family protein -
- 1955756..1955899 - 144 - - Antitoxin
- 1955795..1955897 + 103 - - Toxin
PTQ18_RS09340 1956037..1957116 - 1080 WP_058107134.1 phage integrase Arm DNA-binding domain-containing protein -
PTQ18_RS09345 1957149..1958300 - 1152 Protein_1825 PD-(D/E)XK nuclease-like domain-containing protein -
PTQ18_RS09350 1958289..1958480 + 192 Protein_1826 glycoside hydrolase family 19 protein -
PTQ18_RS09355 1958534..1959067 + 534 WP_023256014.1 DUF2514 domain-containing protein -
PTQ18_RS09360 1959324..1959491 - 168 WP_000789530.1 lytic enzyme -
PTQ18_RS09365 1959556..1959744 - 189 WP_001034748.1 hypothetical protein -
PTQ18_RS09370 1959799..1960059 + 261 Protein_1830 DUF1441 family protein -
PTQ18_RS09375 1960061..1960276 + 216 Protein_1831 shikimate transporter -
PTQ18_RS09380 1960286..1960573 + 288 Protein_1832 macro domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 1932569..1976068 43499
- inside Prophage - sopE2 1932569..1974062 41493


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T272027 NZ_CP117693:1955795-1955897 [Salmonella enterica subsp. enterica serovar London]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT272027 NZ_CP117693:c1955899-1955756 [Salmonella enterica subsp. enterica serovar London]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References