Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3809321..3809579 Replicon chromosome
Accession NZ_CP117668
Organism Escherichia albertii strain BIA_11

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS054_RS18775 Protein ID WP_000809168.1
Coordinates 3809321..3809473 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3809522..3809579 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS054_RS18760 3804732..3806648 + 1917 WP_000516135.1 molecular chaperone DnaK -
PS054_RS18765 3806737..3807867 + 1131 WP_001118445.1 molecular chaperone DnaJ -
PS054_RS18770 3808130..3809243 - 1114 Protein_3656 IS4-like element IS421 family transposase -
PS054_RS18775 3809321..3809473 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 3809522..3809579 + 58 - - Antitoxin
PS054_RS18780 3810095..3810856 + 762 WP_001276206.1 outer membrane protein OmpK -
PS054_RS18785 3810877..3812370 + 1494 WP_273814136.1 sulfatase-like hydrolase/transferase -
PS054_RS18790 3812524..3813771 + 1248 WP_273814138.1 cytoplasmic protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - espX1 3808130..3817709 9579


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271970 WP_000809168.1 NZ_CP117668:c3809473-3809321 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271970 NZ_CP117668:3809522-3809579 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References