Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3706813..3707071 Replicon chromosome
Accession NZ_CP117650
Organism Escherichia albertii strain BIA_16-1

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS055_RS17940 Protein ID WP_000809168.1
Coordinates 3706813..3706965 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3707014..3707071 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS055_RS17925 3702224..3704140 + 1917 WP_059222122.1 molecular chaperone DnaK -
PS055_RS17930 3704229..3705359 + 1131 WP_001118445.1 molecular chaperone DnaJ -
PS055_RS17935 3705622..3706735 - 1114 Protein_3490 IS4-like element IS421 family transposase -
PS055_RS17940 3706813..3706965 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 3707014..3707071 + 58 - - Antitoxin
PS055_RS17945 3707587..3708348 + 762 WP_059220827.1 outer membrane protein OmpK -
PS055_RS17950 3708369..3709856 + 1488 WP_059220825.1 sulfatase-like hydrolase/transferase -
PS055_RS17955 3710016..3711263 + 1248 WP_059220823.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - espX1 3705622..3715201 9579


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271882 WP_000809168.1 NZ_CP117650:c3706965-3706813 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271882 NZ_CP117650:3707014-3707071 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References