Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-timR/SymE(toxin)
Location 531167..531579 Replicon chromosome
Accession NZ_CP117628
Organism Escherichia albertii strain BIA_22

Toxin (Protein)


Gene name symE Uniprot ID -
Locus tag PS041_RS02685 Protein ID WP_044708303.1
Coordinates 531167..531508 (-) Length 114 a.a.

Antitoxin (RNA)


Gene name timR
Locus tag -
Coordinates 531503..531579 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS041_RS02665 (527541) 527541..528473 + 933 WP_273824875.1 Rpn family recombination-promoting nuclease/putative transposase -
PS041_RS02670 (528626) 528626..528799 - 174 Protein_516 GntR family transcriptional regulator -
PS041_RS02675 (529024) 529024..529900 + 877 Protein_517 DUF262 domain-containing protein -
PS041_RS02680 (529954) 529954..531120 + 1167 WP_273824877.1 DUF1524 domain-containing protein -
PS041_RS02685 (531167) 531167..531508 - 342 WP_044708303.1 endoribonuclease SymE Toxin
- (531503) 531503..531579 + 77 NuclAT_10 - Antitoxin
- (531503) 531503..531579 + 77 NuclAT_10 - Antitoxin
- (531503) 531503..531579 + 77 NuclAT_10 - Antitoxin
- (531503) 531503..531579 + 77 NuclAT_10 - Antitoxin
- (531503) 531503..531579 + 77 NuclAT_11 - Antitoxin
- (531503) 531503..531579 + 77 NuclAT_11 - Antitoxin
- (531503) 531503..531579 + 77 NuclAT_11 - Antitoxin
- (531503) 531503..531579 + 77 NuclAT_11 - Antitoxin
PS041_RS02690 (531723) 531723..534986 - 3264 WP_273824879.1 HsdR family type I site-specific deoxyribonuclease -
PS041_RS02695 (535081) 535081..536481 - 1401 WP_059254411.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12384.20 Da        Isoelectric Point: 7.8219

>T271755 WP_044708303.1 NZ_CP117628:c531508-531167 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPTITLKGQWLEAAGFATGTVVDVKVMEGCIVLTTQPPAAEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT271755 NZ_CP117628:531503-531579 [Escherichia albertii]
AGTCATGATTACTATTCTCCATAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References