Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 642464..642722 Replicon chromosome
Accession NZ_CP117620
Organism Escherichia albertii strain BIA_24

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS039_RS03085 Protein ID WP_000809168.1
Coordinates 642464..642616 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 642665..642722 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS039_RS03065 637702..638415 - 714 WP_001102345.1 acidic protein MsyB -
PS039_RS03070 638442..638846 - 405 WP_000833521.1 DUF2541 family protein -
PS039_RS03075 639221..641137 + 1917 WP_000516135.1 molecular chaperone DnaK -
PS039_RS03080 641226..642356 + 1131 WP_273810195.1 molecular chaperone DnaJ -
PS039_RS03085 642464..642616 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 642665..642722 + 58 - - Antitoxin
PS039_RS03090 643239..644000 + 762 WP_001276206.1 outer membrane protein OmpK -
PS039_RS03095 644021..645514 + 1494 WP_059214855.1 sulfatase-like hydrolase/transferase -
PS039_RS03100 645668..646915 + 1248 WP_273810197.1 cytoplasmic protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271729 WP_000809168.1 NZ_CP117620:c642616-642464 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271729 NZ_CP117620:642665-642722 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References