Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-sokC/SymE(toxin)
Location 566757..567169 Replicon chromosome
Accession NZ_CP117620
Organism Escherichia albertii strain BIA_24

Toxin (Protein)


Gene name symE Uniprot ID A0A8D9PK47
Locus tag PS039_RS02715 Protein ID WP_000132619.1
Coordinates 566757..567098 (-) Length 114 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 567093..567169 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS039_RS02695 (561789) 561789..562721 + 933 WP_054409949.1 Rpn family recombination-promoting nuclease/putative transposase -
PS039_RS02700 (563036) 563036..564114 + 1079 Protein_521 DUF1998 domain-containing protein -
PS039_RS02705 (564170) 564170..565216 - 1047 WP_072252312.1 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -
PS039_RS02710 (565216) 565216..566595 - 1380 WP_059217670.1 5-methylcytosine-specific restriction endonuclease subunit McrB -
PS039_RS02715 (566757) 566757..567098 - 342 WP_000132619.1 endoribonuclease SymE Toxin
- (567093) 567093..567169 + 77 NuclAT_6 - Antitoxin
- (567093) 567093..567169 + 77 NuclAT_6 - Antitoxin
- (567093) 567093..567169 + 77 NuclAT_6 - Antitoxin
- (567093) 567093..567169 + 77 NuclAT_6 - Antitoxin
- (567093) 567093..567169 + 77 NuclAT_7 - Antitoxin
- (567093) 567093..567169 + 77 NuclAT_7 - Antitoxin
- (567093) 567093..567169 + 77 NuclAT_7 - Antitoxin
- (567093) 567093..567169 + 77 NuclAT_7 - Antitoxin
PS039_RS02720 (567319) 567319..569094 - 1776 WP_273810174.1 restriction endonuclease subunit S -
PS039_RS02725 (569094) 569094..570563 - 1470 WP_273810175.1 N-6 DNA methylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12322.13 Da        Isoelectric Point: 7.8219

>T271725 WP_000132619.1 NZ_CP117620:c567098-566757 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAPEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT271725 NZ_CP117620:567093-567169 [Escherichia albertii]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References