Detailed information of TA system TA271590

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 32711..33135
• Replicon: plasmid pEA36_4
• Accession: NZ_CP117594
• Organism: Escherichia albertii strain BIA_36

Toxin (Protein)

• Gene name: hok
• Uniprot ID: -
• Locus tag: PS051_RS25375
• Protein ID: WP_223163518.1
• Coordinates: 33013..33135 (+)
• Length: 41 a.a.

Antitoxin (RNA)

Gene name	srnC
Locus tag	-
Coordinates	32711..32909 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PS051_RS25335 (28237)	28237..28530	+	294	WP_273782117.1	hypothetical protein	-
PS051_RS25340 (28596)	28596..29277	+	682	Protein_37	DNA methylase	-
PS051_RS25345 (29278)	29278..29499	+	222	WP_001104873.1	hypothetical protein	-
PS051_RS25350 (29429)	29429..29773	+	345	Protein_39	DUF1380 family protein	-
PS051_RS25355 (29761)	29761..31479	+	1719	Protein_40	ParB/RepB/Spo0J family partition protein	-
PS051_RS25360 (31548)	31548..31982	+	435	WP_000845922.1	conjugation system SOS inhibitor PsiB	-
PS051_RS25365 (31979)	31979..32766	+	788	Protein_42	plasmid SOS inhibition protein A	-
- (32711)	32711..32909	+	199	NuclAT_0	-	Antitoxin
- (32711)	32711..32909	+	199	NuclAT_0	-	Antitoxin
- (32711)	32711..32909	+	199	NuclAT_0	-	Antitoxin
- (32711)	32711..32909	+	199	NuclAT_0	-	Antitoxin
- (32711)	32711..32909	-	199	NuclAT_0	-	-
PS051_RS25370 (32916)	32916..33068	+	153	Protein_43	DUF5431 family protein	-
PS051_RS25375 (33013)	33013..33135	+	123	WP_223163518.1	Hok/Gef family protein	Toxin
PS051_RS25380 (33436)	33436..33733	-	298	Protein_45	hypothetical protein	-
PS051_RS25385 (33908)	33908..34190	+	283	Protein_46	hypothetical protein	-
PS051_RS25390 (34310)	34310..35131	+	822	WP_001234451.1	DUF932 domain-containing protein	-
PS051_RS25395 (35410)	35410..35830	-	421	Protein_48	transglycosylase SLT domain-containing protein	-
PS051_RS25400 (36345)	36345..36740	+	396	WP_001558305.1	conjugal transfer relaxosome DNA-binding protein TraM	-
PS051_RS25405 (36930)	36930..37898	+	969	WP_273780737.1	IS5 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (1-35)

Sequences

Toxin

Protein

• Length: 41 a.a.
• Molecular weight: 4506.32 Da
• Isoelectric Point: 8.2691

>T271590 WP_223163518.1 NZ_CP117594:33013-33135 [Escherichia albertii]
IVCCTLLIFTLLTRNRLCEVRLKDGYREVTASLAYESGGK

Nucleotide

• Length: 123 bp

Antitoxin

Nucleotide

• Length: 199 bp

>AT271590 NZ_CP117594:32711-32909 [Escherichia albertii]
TCACACGGATTGCCCGTGAACTGGCTGAACGACCAGATTATTTTCAGGGAAAGTGAGTGTGGTCAGCGTGCAGGGATATG
GGCTATGATGTGCCCGGCGCTTGAGGCTTTCTGCCTCATGACGTGAAGGTGGTTTGTTACCGTGTTGTGTGGCGGAAGGA
CAAAAGCCCCGTAGTTAATTTTTCATTAACCCACGAGGC

Structures

Antitoxin