Detailed information of TA system TA271580

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 3970979..3971237
• Replicon: chromosome
• Accession: NZ_CP117590
• Organism: Escherichia albertii strain BIA_36

Toxin (Protein)

• Gene name: hokC
• Uniprot ID: -
• Locus tag: PS051_RS19805
• Protein ID: WP_050939643.1
• Coordinates: 3971085..3971237 (+)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokC
Locus tag	-
Coordinates	3970979..3971036 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PS051_RS19785	3966932..3967846	-	915	Protein_3865	sulfatase-like hydrolase/transferase	-
PS051_RS19790	3967930..3969098	+	1169	WP_102203946.1	IS3-like element IS911 family transposase	-
PS051_RS19795	3969108..3969681	-	574	Protein_3867	sulfatase-like hydrolase/transferase	-
PS051_RS19800	3969702..3970463	-	762	WP_273781371.1	outer membrane protein OmpK	-
-	3970979..3971036	-	58	-	-	Antitoxin
PS051_RS19805	3971085..3971237	+	153	WP_050939643.1	type I toxin-antitoxin system toxin MokC	Toxin
PS051_RS19810	3971315..3972427	+	1113	Protein_3870	IS4-like element IS421 family transposase	-
PS051_RS19815	3972690..3973820	-	1131	WP_001118445.1	molecular chaperone DnaJ	-
PS051_RS19820	3973909..3975825	-	1917	WP_000516135.1	molecular chaperone DnaK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	3967930..3972590	4660

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (6-47)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5561.60 Da
• Isoelectric Point: 7.1622

>T271580 WP_050939643.1 NZ_CP117590:3971085-3971237 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLYEVHIRTGQTEVAVFTAYESE

Nucleotide

• Length: 153 bp

>T271580 NZ_CP117590:3971085-3971237 [Escherichia albertii]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTATGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT271580 NZ_CP117590:c3971036-3970979 [Escherichia albertii]
GTTCTTCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Structures

Antitoxin