Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-sib/SymE(toxin)
Location 4355488..4355900 Replicon chromosome
Accession NZ_CP117556
Organism Escherichia albertii strain BIA_89-5

Toxin (Protein)


Gene name symE Uniprot ID A0A8D9PK47
Locus tag PS032_RS21880 Protein ID WP_000132619.1
Coordinates 4355559..4355900 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name sib
Locus tag -
Coordinates 4355488..4355564 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS032_RS21870 (4352360) 4352360..4353949 + 1590 WP_074463834.1 type I restriction-modification system methyltransferase -
PS032_RS21875 (4353946) 4353946..4355331 + 1386 WP_059257978.1 restriction endonuclease subunit S -
- (4355488) 4355488..4355564 - 77 NuclAT_8 - Antitoxin
- (4355488) 4355488..4355564 - 77 NuclAT_8 - Antitoxin
- (4355488) 4355488..4355564 - 77 NuclAT_8 - Antitoxin
- (4355488) 4355488..4355564 - 77 NuclAT_8 - Antitoxin
- (4355488) 4355488..4355564 - 77 NuclAT_9 - Antitoxin
- (4355488) 4355488..4355564 - 77 NuclAT_9 - Antitoxin
- (4355488) 4355488..4355564 - 77 NuclAT_9 - Antitoxin
- (4355488) 4355488..4355564 - 77 NuclAT_9 - Antitoxin
PS032_RS21880 (4355559) 4355559..4355900 + 342 WP_000132619.1 endoribonuclease SymE Toxin
PS032_RS21885 (4356062) 4356062..4357441 + 1380 WP_059217670.1 5-methylcytosine-specific restriction endonuclease subunit McrB -
PS032_RS21890 (4357441) 4357441..4358487 + 1047 WP_074463833.1 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -
PS032_RS21895 (4358543) 4358543..4359621 - 1079 Protein_4280 DUF1998 domain-containing protein -
PS032_RS21900 (4359936) 4359936..4360868 - 933 Protein_4281 Rpn family recombination-promoting nuclease/putative transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12322.13 Da        Isoelectric Point: 7.8219

>T271352 WP_000132619.1 NZ_CP117556:4355559-4355900 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAPEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT271352 NZ_CP117556:c4355564-4355488 [Escherichia albertii]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References