Detailed information of TA system TA271003

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/SymE(toxin)
• Location: 3685373..3685787
• Replicon: chromosome
• Accession: NZ_CP117384
• Organism: Salmonella enterica subsp. enterica serovar Uganda strain RM013

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: PQP89_RS18230
• Protein ID: WP_079798500.1
• Coordinates: 3685530..3685787 (+)
• Length: 86 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3685373..3685705 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PQP89_RS18200	3681602..3682339	-	738	WP_001750707.1	pili assembly chaperone SafB	-
PQP89_RS18205	3682416..3682913	-	498	WP_001750706.1	Saf-pilin pilus formation protein SafA	-
PQP89_RS18210	3683674..3684378	-	705	Protein_3562	integrase core domain-containing protein	-
PQP89_RS18215	3684431..3684679	+	249	WP_001738030.1	SymE family type I addiction module toxin	-
PQP89_RS18220	3684811..3685089	-	279	WP_079798501.1	hypothetical protein	-
PQP89_RS18225	3685172..3685288	-	117	WP_227457392.1	hypothetical protein	-
-	3685373..3685705	-	333	-	-	Antitoxin
PQP89_RS18230	3685530..3685787	+	258	WP_079798500.1	SymE family type I addiction module toxin	Toxin
PQP89_RS18235	3685878..3686255	-	378	WP_000739707.1	Imm8 family immunity protein	-
PQP89_RS18240	3686988..3687353	-	366	WP_001231281.1	hypothetical protein	-
PQP89_RS18245	3687319..3688665	-	1347	Protein_3569	RHS repeat-associated core domain-containing protein	-
PQP89_RS18250	3688727..3688984	+	258	WP_000994229.1	SymE family type I addiction module toxin	-
PQP89_RS18255	3689048..3689386	-	339	WP_000382983.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3665186..3694527	29341
	-	flank	IS/Tn	-	-	3683674..3683955	281

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (14-56)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 9547.82 Da
• Isoelectric Point: 5.0770

>T271003 WP_079798500.1 NZ_CP117384:3685530-3685787 [Salmonella enterica subsp. enterica serovar Uganda]
MNASGVSVRHINSETCMSACYSQIPSQHLKGDWQEEAGFETGRSITVKISQECIVLMADSNEEQKLREQLYKAEQVVKGM
RDVIV

Nucleotide

• Length: 258 bp

Antitoxin

Nucleotide

• Length: 333 bp

>AT271003 NZ_CP117384:c3685705-3685373 [Salmonella enterica subsp. enterica serovar Uganda]
TCCGCCATCAGCACAATACACTCCTGTGAAATCTTCACGGTGATGCTGCGCCCGGTCTCAAATCCCGCTTCTTCCTGCCA
GTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGACATGCAGGTTTCGCTGTTGATATGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCAGCCGGCTGCC
GGGGCCGTATTTT

Structures

Antitoxin