Detailed information of TA system TA027032

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 3663844..3664513
• Replicon: chromosome
• Accession: NC_017571
• Organism: Shewanella baltica BA175

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: G0AWZ0
• Locus tag: SBAL175_RS22785
• Protein ID: WP_006080771.1
• Coordinates: 3663844..3664284 (-)
• Length: 147 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: SBAL175_RS15730
• Protein ID: WP_006080770.1
• Coordinates: 3664265..3664513 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SBAL175_RS15705	3659296..3659769	-	474	WP_006080776.1	SoxR reducing system RseC family protein	-
SBAL175_RS15710	3659780..3660712	-	933	WP_006080775.1	MucB/RseB C-terminal domain-containing protein	-
SBAL175_RS15715	3660725..3661351	-	627	WP_006080774.1	anti-sigma factor	-
SBAL175_RS15720	3661393..3661971	-	579	WP_006080773.1	RNA polymerase sigma factor RpoE	-
SBAL175_RS15725	3662162..3663775	+	1614	WP_006080772.1	L-aspartate oxidase	-
SBAL175_RS22785	3663844..3664284	-	441	WP_006080771.1	hypothetical protein	Toxin
SBAL175_RS15730	3664265..3664513	-	249	WP_006080770.1	succinate dehydrogenase assembly factor 2	Antitoxin
SBAL175_RS15735	3664599..3665507	-	909	WP_006080769.1	transcriptional activator NhaR	-
SBAL175_RS15740	3665580..3665966	-	387	WP_006080768.1	hypothetical protein	-
SBAL175_RS15745	3665969..3667138	-	1170	WP_006080767.1	Na+/H+ antiporter NhaA	-
SBAL175_RS15750	3667256..3668050	-	795	WP_006080766.1	thymidylate synthase	-
SBAL175_RS15755	3668047..3668856	-	810	WP_006080765.1	prolipoprotein diacylglyceryl transferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (7-135)

Antitoxin

• Flavinator of succinate dehydrogenase (7-77)

Sequences

Toxin

Protein

• Length: 147 a.a.
• Molecular weight: 17324.44 Da
• Isoelectric Point: 7.7165

>T27032 WP_006080771.1 NC_017571:c3664284-3663844 [Shewanella baltica BA175]
VEDRHHSFILKASFDQRLSLVVFICVCSSSFLLWPQSDNLALSLLKYLFILLVCVFLLSQLWRLQHWRLDFVLSDKGEGR
LSTGEHFQVLKRTWVTPFVCLMYIEVDTQLRLLMVWADMLDDTDYRHLCRLLLRAKIQQTKPHTEI

Nucleotide

• Length: 441 bp

>T27032 NC_017571:c3664284-3663844 [Shewanella baltica BA175]
GTGGAAGACCGGCACCATAGTTTCATCTTAAAAGCCTCCTTCGACCAACGACTCTCGTTGGTCGTTTTTATTTGTGTCTG
TTCTAGCTCATTTTTACTCTGGCCCCAGAGCGATAATCTCGCCTTATCCCTGCTTAAATATCTGTTTATCCTGCTAGTTT
GTGTTTTCTTGCTATCACAGTTGTGGCGACTGCAGCATTGGCGTTTAGATTTTGTGCTTAGTGATAAAGGCGAGGGACGT
TTGTCAACGGGTGAGCACTTTCAGGTATTAAAGCGAACTTGGGTGACCCCCTTTGTTTGCTTGATGTATATCGAAGTGGA
TACTCAGTTGCGGCTCTTGATGGTTTGGGCGGATATGCTAGACGATACTGACTATCGGCATTTATGTCGGCTGTTGCTGC
GGGCTAAAATACAACAGACTAAACCTCATACTGAGATTTAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9723.36 Da
• Isoelectric Point: 4.4929

>AT27032 WP_006080770.1 NC_017571:c3664513-3664265 [Shewanella baltica BA175]
MELMNIARVRWACRRGMLELDVLFQPFVENFYQEMSDEDKTVFIRLLECEDPELFAWFMGHEVCPDAELARMVVKVRGRP
AP

Nucleotide

• Length: 249 bp

>AT27032 NC_017571:c3664513-3664265 [Shewanella baltica BA175]
TTGGAATTAATGAACATCGCAAGGGTTCGCTGGGCATGTCGCCGCGGGATGCTGGAATTAGACGTTTTGTTTCAACCTTT
TGTTGAAAACTTCTATCAAGAAATGTCCGATGAAGATAAAACCGTGTTTATCCGTTTGTTGGAATGTGAAGATCCCGAAT
TGTTTGCATGGTTTATGGGCCATGAAGTTTGCCCTGATGCTGAACTCGCGCGTATGGTAGTGAAAGTCCGTGGAAGACCG
GCACCATAG

Structures

Toxin

• AlphaFold DB: G0AWZ0