Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2778220..2778363 Replicon chromosome
Accession NZ_CP117294
Organism Salmonella enterica subsp. enterica serovar Typhi strain S1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2778222..2778324 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2778220..2778363 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PRW94_RS13890 (PRW94_13890) 2775498..2776628 + 1131 WP_000529513.1 GGDEF domain-containing protein -
PRW94_RS13895 (PRW94_13895) 2776914..2777309 - 396 Protein_2723 DUF977 family protein -
PRW94_RS13900 (PRW94_13900) 2777322..2777432 - 111 Protein_2724 replication protein -
PRW94_RS13905 (PRW94_13905) 2777433..2777794 + 362 Protein_2725 recombinase RecT -
PRW94_RS13910 (PRW94_13910) 2777793..2778101 + 309 Protein_2726 tyrosine-type recombinase/integrase -
- 2778220..2778363 + 144 - - Antitoxin
- 2778222..2778324 - 103 - - Toxin
PRW94_RS13915 (PRW94_13915) 2778465..2778818 - 354 WP_000722366.1 YebY family protein -
PRW94_RS13920 (PRW94_13920) 2778835..2779710 - 876 WP_000979693.1 copper homeostasis membrane protein CopD -
PRW94_RS13925 (PRW94_13925) 2779711..2780085 - 375 WP_001681742.1 CopC domain-containing protein YobA -
PRW94_RS13930 (PRW94_13930) 2780223..2780453 + 231 WP_000856224.1 DNA polymerase III subunit theta -
PRW94_RS13935 (PRW94_13935) 2780561..2781217 + 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
PRW94_RS13940 (PRW94_13940) 2781241..2781939 + 699 WP_000944282.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2754681..2784027 29346


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T270305 NZ_CP117294:c2778324-2778222 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT270305 NZ_CP117294:2778220-2778363 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References