Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2776578..2776721 Replicon chromosome
Accession NZ_CP117293
Organism Salmonella enterica subsp. enterica serovar Typhi strain S2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2776580..2776682 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2776578..2776721 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PRW95_RS13885 (PRW95_13885) 2773856..2774986 + 1131 WP_000529513.1 GGDEF domain-containing protein -
PRW95_RS13890 (PRW95_13890) 2775272..2775667 - 396 Protein_2722 DUF977 family protein -
PRW95_RS13895 (PRW95_13895) 2775680..2775790 - 111 Protein_2723 replication protein -
PRW95_RS13900 (PRW95_13900) 2775791..2776152 + 362 Protein_2724 recombinase RecT -
PRW95_RS13905 (PRW95_13905) 2776151..2776459 + 309 Protein_2725 tyrosine-type recombinase/integrase -
- 2776578..2776721 + 144 - - Antitoxin
- 2776580..2776682 - 103 - - Toxin
PRW95_RS13910 (PRW95_13910) 2776823..2777176 - 354 WP_000722366.1 YebY family protein -
PRW95_RS13915 (PRW95_13915) 2777193..2778068 - 876 WP_000979693.1 copper homeostasis membrane protein CopD -
PRW95_RS13920 (PRW95_13920) 2778069..2778443 - 375 WP_001681742.1 CopC domain-containing protein YobA -
PRW95_RS13925 (PRW95_13925) 2778581..2778811 + 231 WP_000856224.1 DNA polymerase III subunit theta -
PRW95_RS13930 (PRW95_13930) 2778919..2779575 + 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
PRW95_RS13935 (PRW95_13935) 2779599..2780297 + 699 WP_000944282.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2745391..2798594 53203


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T270290 NZ_CP117293:c2776682-2776580 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT270290 NZ_CP117293:2776578-2776721 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References