Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2551002..2551273 Replicon chromosome
Accession NZ_CP116981
Organism Escherichia coli strain E6474

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2551040..2551143 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2551002..2551273 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO910_RS12410 2548159..2549598 + 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
PO910_RS12415 2549716..2549952 + 237 WP_001295499.1 YebV family protein -
PO910_RS12420 2550057..2550248 + 192 WP_001296140.1 YebW family protein -
PO910_RS12425 2550249..2550905 - 657 WP_000812734.1 protein-serine/threonine phosphatase -
- 2551002..2551273 + 272 - - Antitoxin
- 2551040..2551143 - 104 - - Toxin
PO910_RS12430 2551301..2551642 - 342 WP_000976492.1 YebY family protein -
PO910_RS12435 2551655..2552527 - 873 WP_000879285.1 copper homeostasis membrane protein CopD -
PO910_RS12440 2552531..2552905 - 375 WP_000204699.1 CopC domain-containing protein YobA -
PO910_RS12445 2553044..2553274 + 231 WP_000916763.1 DNA polymerase III subunit theta -
PO910_RS12450 2553376..2554032 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
PO910_RS12455 2554056..2554718 + 663 WP_124053605.1 exodeoxyribonuclease X -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 104 bp

>T269627 NZ_CP116981:c2551143-2551040 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT269627 NZ_CP116981:2551002-2551273 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References