Detailed information of TA system TA026943

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 3631917..3632818
• Replicon: chromosome
• Accession: NC_017530
• Organism: Pseudomonas putida BIRD-1

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PPUBIRD1_RS16455
• Protein ID: WP_041167030.1
• Coordinates: 3631917..3632372 (-)
• Length: 152 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A524BX56
• Locus tag: PPUBIRD1_RS16460
• Protein ID: WP_014591577.1
• Coordinates: 3632369..3632818 (-)
• Length: 150 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PPUBIRD1_RS16440	3627967..3629196	-	1230	WP_003250533.1	acyl-CoA dehydrogenase	-
PPUBIRD1_RS16445	3629337..3630263	+	927	WP_014591574.1	LysR family transcriptional regulator	-
PPUBIRD1_RS16450	3630457..3631611	+	1155	WP_041167181.1	aminotransferase class V-fold PLP-dependent enzyme	-
PPUBIRD1_RS16455	3631917..3632372	-	456	WP_041167030.1	RES family NAD+ phosphorylase	Toxin
PPUBIRD1_RS16460	3632369..3632818	-	450	WP_014591577.1	DUF2384 domain-containing protein	Antitoxin
PPUBIRD1_RS16465	3632960..3633613	-	654	WP_014591578.1	oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB	-
PPUBIRD1_RS16470	3633717..3634640	+	924	WP_014591579.1	LysR family transcriptional regulator	-
PPUBIRD1_RS16475	3634689..3635519	+	831	WP_003250518.1	AraC family transcriptional regulator	-
PPUBIRD1_RS16480	3635570..3636154	+	585	WP_014591580.1	LysE family transporter	-
PPUBIRD1_RS16485	3636194..3637393	-	1200	WP_014591581.1	sugar transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-138)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (97-146)

Sequences

Toxin

Protein

• Length: 152 a.a.
• Molecular weight: 16581.94 Da
• Isoelectric Point: 6.4820

>T26943 WP_041167030.1 NC_017530:c3632372-3631917 [Pseudomonas putida BIRD-1]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSAQPELTRTLGNRFLDDGSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLSSVVFHK

Nucleotide

• Length: 456 bp

>T26943 NC_017530:c3632372-3631917 [Pseudomonas putida BIRD-1]
GTGATTTTGTGGCGAATCAGCGCCTATGCAGACTTGAGCGGTACGGGGGGCTTGCGTGTAAGTGGCCGCTGGCACCAGGC
GGGTCGGCCAGTGGTGTATGCCGCCACCAGCCCTCCCGGGGCGATGCTGGAAGTGTTGGTGCACCTGGAGATCGACCCCG
AAGATTTCCCTACCACCATGCGCTTGCTGCGCATCGAACTGCCCGACACGGTTTCCCAGGCGCAGTTGCCCGCTTTGCAG
CCCGGCTGGTCTGCCCAACCTGAGTTGACCCGTACGCTGGGCAATCGCTTTCTGGATGACGGTTCGGCATTGCTGCTGCC
GGTGCCAAGCGCGATCATGCCCAGCACTACCAATTACCTGTTCAACCCACGGCACCCACAGGCGCAGAGCGCGAAAATCC
AGGTTGAGGATTTCACGCCGGACAGCCGCCTGTCTAGTGTGGTGTTTCACAAATAA

Antitoxin

Protein

• Length: 150 a.a.
• Molecular weight: 16984.51 Da
• Isoelectric Point: 5.7258

>AT26943 WP_014591577.1 NC_017530:c3632818-3632369 [Pseudomonas putida BIRD-1]
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEVGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL

Nucleotide

• Length: 450 bp

>AT26943 NC_017530:c3632818-3632369 [Pseudomonas putida BIRD-1]
ATGCTTGCCGAAGTGCTACGCGACAACGGTTACCACGAGTACCGGGCGCGCTTGCAGGCGCTGCTGGACATTCCCGAGCT
TGCCAGCGACTTCGAAATCCACACCCGCATCACCGATGGTTTTGCCGCCACCTGGTTGGTAAAGCTGACTGAACGCGGTG
TGCTCACGCCGGTGGAGCGCGACCAGATCATTCCGCTGCGCACCCTCAAATCCCGTATCGAGCGTGACCAACCGCTGACC
GTGGATGAGAGCGACCGGCTGTTCCGCTCGGCCCACATCACCGCCATGGCCGAGGCTGTGTTCGGGGAAGTGGGCAAGGC
CAAACGCTGGCTTTCCAAGCCTAAGGAACGCTTCTCGGGGCTGACGCCGATGCAGATGCTCACCACCCAGCAAGGCACCA
CGCAGGTCGAAGAAATGCTGCTGCAGATTGCCGAGGGCTATGGCCTGTGA

Structures

Antitoxin

• AlphaFold DB: A0A524BX56