Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2191130..2191401 Replicon chromosome
Accession NZ_CP116919
Organism Escherichia coli strain MLI102

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2191260..2191363 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2191130..2191401 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL418_RS11215 2187685..2188347 - 663 WP_000944256.1 exodeoxyribonuclease X -
NL418_RS11220 2188371..2189027 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
NL418_RS11225 2189129..2189359 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NL418_RS11230 2189498..2189872 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NL418_RS11235 2189876..2190748 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
NL418_RS11240 2190761..2191102 + 342 WP_000976472.1 YebY family protein -
- 2191130..2191401 - 272 - - Antitoxin
- 2191260..2191363 + 104 - - Toxin
NL418_RS11245 2191498..2192154 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
NL418_RS11250 2192155..2192346 - 192 WP_001296140.1 YebW family protein -
NL418_RS11255 2192451..2192687 - 237 WP_001295499.1 YebV family protein -
NL418_RS11260 2192805..2194244 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T269417 NZ_CP116919:2191260-2191363 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT269417 NZ_CP116919:c2191401-2191130 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References