Detailed information of TA system TA026941

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 1868857..1869557
• Replicon: chromosome
• Accession: NC_017530
• Organism: Pseudomonas putida BIRD-1

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: PPUBIRD1_RS08285
• Protein ID: WP_041166873.1
• Coordinates: 1868857..1869153 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: I7AUJ7
• Locus tag: PPUBIRD1_RS08290
• Protein ID: WP_003254235.1
• Coordinates: 1869156..1869557 (+)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PPUBIRD1_RS08265	1864849..1866027	-	1179	WP_014590258.1	efflux RND transporter periplasmic adaptor subunit	-
PPUBIRD1_RS08270	1866240..1866716	+	477	WP_014590259.1	sigma-70 family RNA polymerase sigma factor	-
PPUBIRD1_RS08275	1866885..1867364	+	480	WP_014590260.1	hypothetical protein	-
PPUBIRD1_RS08280	1867437..1868762	+	1326	WP_014590261.1	MFS transporter	-
PPUBIRD1_RS08285	1868857..1869153	+	297	WP_041166873.1	type II toxin-antitoxin system MqsR family toxin	Toxin
PPUBIRD1_RS08290	1869156..1869557	+	402	WP_003254235.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
PPUBIRD1_RS08295	1869633..1871315	-	1683	WP_080557776.1	electron transfer flavoprotein-ubiquinone oxidoreductase	-
PPUBIRD1_RS08300	1871851..1872600	+	750	WP_014590265.1	electron transfer flavoprotein subunit beta/FixA family protein	-
PPUBIRD1_RS08305	1872601..1873530	+	930	WP_003254230.1	FAD-binding protein	-
PPUBIRD1_RS08310	1873606..1874427	+	822	WP_014590266.1	transporter substrate-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (6-97)

Antitoxin

• Cro/C1-type helix-turn-helix domain (74-109)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11105.16 Da
• Isoelectric Point: 10.0317

>T26941 WP_041166873.1 NC_017530:1868857-1869153 [Pseudomonas putida BIRD-1]
MEKRMPHCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHQVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL

Nucleotide

• Length: 297 bp

>T26941 NC_017530:1868857-1869153 [Pseudomonas putida BIRD-1]
ATGGAAAAGAGAATGCCTCATTGCCCGCTGGAGCGGGTAAAAGCCCTGGCTGCGGCAAGGCGAATCCGTCCTACGGGTGC
TGCATTGAAAGGCGCCAAGGCGCTGGGAATGGATTTTCCGGGCATGCTTGAGGTGATCACCAGCTTAAAGCGCACTGATT
TCTACAAGAGCATGACCAGCCATATTGACCACCAGGTTTGGCAGGATGTGTATCGCCCGCTTACAGCAATTGGGTACGTT
TATTTGAAATTGTCCGTGGTAGACGACGTGCTCATCGTGTCTTTCAAGGAGTTGTAA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14684.76 Da
• Isoelectric Point: 4.9531

>AT26941 WP_003254235.1 NC_017530:1869156-1869557 [Pseudomonas putida BIRD-1]
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Nucleotide

• Length: 402 bp

>AT26941 NC_017530:1869156-1869557 [Pseudomonas putida BIRD-1]
ATGAGATGTCCAATATGCGGCGGCTCGGAGCTTGCACCTGACATTCAGGGCATGCCCTATAGCTACAAAGGCGAGATGAC
AGTGATCCCGGAGGTAAGTGGCGATTACTGCTCTGCATGTGGTGAATGCGTACTGAGTCATGATGAAGCCATGCGCGTCA
GTCACTTGATGACGGCATTCGAGCGCCAGGTCAACGCAAATGTTGTGGATCCTTCCTTTATTGCCTCCATACGCAGAAAG
TTCGACCTCGACCAGCGTGAAGCGGGGGAAATCTTCGGTGGTGGGGTCAATGCGTTCTCCCGTTATGAAAACGGCAAGAC
CACCCCGCCAGTGGCGTTGGTGAAACTGCTCAAGCTGCTGGATCGCCATCCAGAACTCTTTGAGGAAGTGCGTACTGCCT
GA

Structures

Antitoxin

• AlphaFold DB: I7AUJ7