Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2219804..2219949 Replicon chromosome
Accession NZ_CP116903
Organism Klebsiella pneumoniae strain KP2722

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2219840..2219942 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2219804..2219949 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO783_RS10945 (PO783_10945) 2214934..2216994 + 2061 WP_004151449.1 oligopeptidase B -
PO783_RS10950 (PO783_10950) 2216998..2217657 - 660 WP_002911407.1 exodeoxyribonuclease X -
PO783_RS10955 (PO783_10955) 2217736..2217966 - 231 WP_002911406.1 DNA polymerase III subunit theta -
PO783_RS10960 (PO783_10960) 2218079..2218453 + 375 WP_004151448.1 CopC domain-containing protein YobA -
PO783_RS10965 (PO783_10965) 2218457..2219326 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
PO783_RS10970 (PO783_10970) 2219343..2219681 + 339 WP_002911404.1 YebY family protein -
- 2219804..2219949 - 146 - - Antitoxin
- 2219840..2219942 + 103 - - Toxin
PO783_RS10975 (PO783_10975) 2220317..2220460 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
PO783_RS10980 (PO783_10980) 2220565..2221533 - 969 WP_004151446.1 VirK/YbjX family protein -
PO783_RS10985 (PO783_10985) 2221690..2222343 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
PO783_RS10990 (PO783_10990) 2222340..2222531 - 192 WP_002911395.1 YebW family protein -
PO783_RS10995 (PO783_10995) 2222629..2222868 - 240 WP_002911393.1 YebV family protein -
PO783_RS11000 (PO783_11000) 2222984..2224417 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T269341 NZ_CP116903:2219840-2219942 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT269341 NZ_CP116903:c2219949-2219804 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References