Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 2552124..2552639 Replicon chromosome
Accession NZ_CP116672
Organism Xanthomonas hortorum pv. pelargonii strain 305

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PML25_RS10515 Protein ID WP_168958820.1
Coordinates 2552124..2552330 (+) Length 69 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PML25_RS10520 Protein ID WP_168958821.1
Coordinates 2552340..2552639 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PML25_RS10490 (PML25_10490) 2547350..2547658 - 309 WP_023903904.1 STAS domain-containing protein -
PML25_RS10495 (PML25_10495) 2547762..2548997 - 1236 WP_168958819.1 chemotaxis protein CheW -
PML25_RS10500 (PML25_10500) 2548994..2549776 - 783 WP_006452730.1 ParA family protein -
PML25_RS10505 (PML25_10505) 2549778..2550752 - 975 WP_023903906.1 flagellar motor protein MotD -
PML25_RS10510 (PML25_10510) 2550760..2551500 - 741 WP_006452732.1 flagellar motor protein -
PML25_RS10515 (PML25_10515) 2552124..2552330 + 207 WP_168958820.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PML25_RS10520 (PML25_10520) 2552340..2552639 + 300 WP_168958821.1 HigA family addiction module antitoxin Antitoxin
PML25_RS10525 (PML25_10525) 2552850..2554997 - 2148 WP_168958822.1 TonB-dependent receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(3-68)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(4-88)


Sequences

Toxin        


Download         Length: 69 a.a.        Molecular weight: 7652.65 Da        Isoelectric Point: 6.7129

>T269092 WP_168958820.1 NZ_CP116672:2552124-2552330 [Xanthomonas hortorum pv. pelargonii]
MQAVAERKLQLLGSAQTLEFLRSPPGNRLELLAGTRAGQHSSRINDQWRVCVVWTDAGPEHVEIVDYH

Download         Length: 207 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10930.70 Da        Isoelectric Point: 12.0093

>AT269092 WP_168958821.1 NZ_CP116672:2552340-2552639 [Xanthomonas hortorum pv. pelargonii]
MRPTNKLRAIHPGEILRKDFMLPLGLTINGLARALDVPATRIHSIVHGERAISADTAARLARHFGGDAASWLALRATHDL
KTLPNRSEIERNVRPRVVA

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References