Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2018123..2018268 Replicon chromosome
Accession NZ_CP116491
Organism Klebsiella pneumoniae strain XY05-03

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2018159..2018261 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2018123..2018268 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PIB23_RS09885 (PIB23_09885) 2013253..2015313 + 2061 WP_004151449.1 oligopeptidase B -
PIB23_RS09890 (PIB23_09890) 2015317..2015976 - 660 WP_002911407.1 exodeoxyribonuclease X -
PIB23_RS09895 (PIB23_09895) 2016055..2016285 - 231 WP_002911406.1 DNA polymerase III subunit theta -
PIB23_RS09900 (PIB23_09900) 2016398..2016772 + 375 WP_004151448.1 CopC domain-containing protein YobA -
PIB23_RS09905 (PIB23_09905) 2016776..2017645 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
PIB23_RS09910 (PIB23_09910) 2017662..2018000 + 339 WP_002911404.1 YebY family protein -
- 2018123..2018268 - 146 - - Antitoxin
- 2018159..2018261 + 103 - - Toxin
PIB23_RS09915 (PIB23_09915) 2018636..2018779 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
PIB23_RS09920 (PIB23_09920) 2018884..2019852 - 969 WP_004151446.1 VirK/YbjX family protein -
PIB23_RS09925 (PIB23_09925) 2020009..2020662 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
PIB23_RS09930 (PIB23_09930) 2020659..2020850 - 192 WP_002911395.1 YebW family protein -
PIB23_RS09935 (PIB23_09935) 2020948..2021187 - 240 WP_002911393.1 YebV family protein -
PIB23_RS09940 (PIB23_09940) 2021303..2022736 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T268792 NZ_CP116491:2018159-2018261 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT268792 NZ_CP116491:c2018268-2018123 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References