Detailed information of TA system
Overview
TA module
| Type | III | Classification (family/domain) | toxIN/ToxN(toxin) |
| Location | 412576..413318 | Replicon | plasmid pLip457 |
| Accession | NZ_CP116318 | ||
| Organism | Bacillus thuringiensis strain Lip | ||
Toxin (Protein)
| Gene name | toxN | Uniprot ID | - |
| Locus tag | PJW02_RS30970 | Protein ID | WP_016097319.1 |
| Coordinates | 412734..413318 (+) | Length | 195 a.a. |
Antitoxin (RNA)
| Gene name | toxI | ||
| Locus tag | - | ||
| Coordinates | 412576..412672 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PJW02_RS30950 (408126) | 408126..409757 | + | 1632 | WP_016097315.1 | ArdC-like ssDNA-binding domain-containing protein | - |
| PJW02_RS30955 (409819) | 409819..410805 | + | 987 | WP_016097316.1 | hypothetical protein | - |
| PJW02_RS30960 (410827) | 410827..411378 | + | 552 | WP_016097317.1 | metal-dependent hydrolase | - |
| PJW02_RS30965 (411458) | 411458..412483 | + | 1026 | WP_016097318.1 | DUF3991 and TOPRIM domain-containing protein | - |
| - (412576) | 412576..412672 | + | 97 | NuclAT_0 | - | Antitoxin |
| - (412576) | 412576..412672 | + | 97 | NuclAT_0 | - | Antitoxin |
| - (412576) | 412576..412672 | + | 97 | NuclAT_0 | - | Antitoxin |
| - (412576) | 412576..412672 | + | 97 | NuclAT_0 | - | Antitoxin |
| PJW02_RS30970 (412734) | 412734..413318 | + | 585 | WP_016097319.1 | type III toxin-antitoxin system ToxN/AbiQ family toxin | Toxin |
| PJW02_RS30975 (413386) | 413386..414687 | + | 1302 | WP_016097320.1 | hypothetical protein | - |
| PJW02_RS30980 (414794) | 414794..415174 | + | 381 | WP_016097321.1 | hypothetical protein | - |
| PJW02_RS30985 (415295) | 415295..417436 | + | 2142 | WP_016097322.1 | type IA DNA topoisomerase | - |
| PJW02_RS30990 (417466) | 417466..417912 | + | 447 | WP_016097323.1 | CPBP family intramembrane metalloprotease | - |
| PJW02_RS30995 (418065) | 418065..418235 | - | 171 | WP_016097324.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..457481 | 457481 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 195 a.a. Molecular weight: 22900.17 Da Isoelectric Point: 8.9694
>T268589 WP_016097319.1 NZ_CP116318:412734-413318 [Bacillus thuringiensis]
MANKDNPKFYTISTEYIDYLRETDSKVPFNKDEQHSRPYVGVLEKINGHDYFVPLTSRNDKNFNSQVSVKLFDTDEKRIG
VLLVNNMIPVPEKECKEIDIAEKTAADPQYGNLMLKQYLFLKENMDRVTNKVEKVYKDVTVQGKPSHKQKFLKGVCCDFP
KLEEKCQEYKERDQAKERDKARRIAYMRQMGRER
MANKDNPKFYTISTEYIDYLRETDSKVPFNKDEQHSRPYVGVLEKINGHDYFVPLTSRNDKNFNSQVSVKLFDTDEKRIG
VLLVNNMIPVPEKECKEIDIAEKTAADPQYGNLMLKQYLFLKENMDRVTNKVEKVYKDVTVQGKPSHKQKFLKGVCCDFP
KLEEKCQEYKERDQAKERDKARRIAYMRQMGRER
Download Length: 585 bp
Antitoxin
Download Length: 97 bp
>AT268589 NZ_CP116318:412576-412672 [Bacillus thuringiensis]
GTAACCTTACTTTAGTAGGTGCGAAAAAATTGGTGTAACTCTACCGTAGTGAGTACCAAAAAATTGGTGTAGCCTTACCG
TAGTAGGCGCTAAAAAA
GTAACCTTACTTTAGTAGGTGCGAAAAAATTGGTGTAACTCTACCGTAGTGAGTACCAAAAAATTGGTGTAGCCTTACCG
TAGTAGGCGCTAAAAAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
