Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1776140..1776653 Replicon chromosome
Accession NZ_CP116303
Organism Tenacibaculum finnmarkense strain 20-4106-2

Toxin (Protein)


Gene name relE Uniprot ID A0A2H1YD11
Locus tag PJH08_RS07710 Protein ID WP_058885305.1
Coordinates 1776396..1776653 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2H1YCK0
Locus tag PJH08_RS07705 Protein ID WP_058885304.1
Coordinates 1776140..1776394 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJH08_RS07690 (PJH08_07690) 1771328..1772176 + 849 WP_233885030.1 IS3 family transposase -
PJH08_RS07695 (PJH08_07695) 1772264..1772839 + 576 WP_271402629.1 hypothetical protein -
PJH08_RS07700 (PJH08_07700) 1772932..1774212 - 1281 WP_193708134.1 group II intron reverse transcriptase/maturase -
PJH08_RS07705 (PJH08_07705) 1776140..1776394 + 255 WP_058885304.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PJH08_RS07710 (PJH08_07710) 1776396..1776653 + 258 WP_058885305.1 Txe/YoeB family addiction module toxin Toxin
PJH08_RS07715 (PJH08_07715) 1776749..1778029 - 1281 WP_193708134.1 group II intron reverse transcriptase/maturase -
PJH08_RS07720 (PJH08_07720) 1778702..1779220 + 519 WP_271402630.1 hypothetical protein -
PJH08_RS07725 (PJH08_07725) 1779430..1780476 + 1047 WP_101915774.1 hypothetical protein -
PJH08_RS07730 (PJH08_07730) 1780480..1781103 + 624 WP_101915773.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10475.04 Da        Isoelectric Point: 9.7333

>T268577 WP_058885305.1 NZ_CP116303:1776396-1776653 [Tenacibaculum finnmarkense]
MKYTFVDESWEDYLYWQKTDKKKLKKINELLKDIARNPFDGIGKPEALKHKYAGFWSRRIDSEHRLIYQYREGEILIAKC
RFHYN

Download         Length: 258 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9677.10 Da        Isoelectric Point: 7.0115

>AT268577 WP_058885304.1 NZ_CP116303:1776140-1776394 [Tenacibaculum finnmarkense]
MQITTVSDFRKDIKSYLDRVIKDFETLIINRGKDSGIVVMSLQEYNSLMATNHELSSRKNELRLDSAIDKLKNGMTLNKD
LIEN

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2H1YD11

Antitoxin

Source ID Structure
AlphaFold DB A0A2H1YCK0

References