Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1734386..1734973 Replicon chromosome
Accession NZ_CP116303
Organism Tenacibaculum finnmarkense strain 20-4106-2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PJH08_RS07540 Protein ID WP_271402616.1
Coordinates 1734386..1734685 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PJH08_RS07545 Protein ID WP_101902711.1
Coordinates 1734689..1734973 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJH08_RS07520 (PJH08_07520) 1729564..1729956 + 393 WP_101915088.1 helix-turn-helix domain-containing protein -
PJH08_RS07525 (PJH08_07525) 1729971..1730819 + 849 WP_233885030.1 IS3 family transposase -
PJH08_RS07530 (PJH08_07530) 1730870..1731625 + 756 WP_271402615.1 hypothetical protein -
PJH08_RS07535 (PJH08_07535) 1731781..1732389 + 609 WP_232125636.1 SMI1/KNR4 family protein -
PJH08_RS07540 (PJH08_07540) 1734386..1734685 + 300 WP_271402616.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PJH08_RS07545 (PJH08_07545) 1734689..1734973 + 285 WP_101902711.1 putative addiction module antidote protein Antitoxin
PJH08_RS07550 (PJH08_07550) 1735856..1736248 + 393 WP_101915088.1 helix-turn-helix domain-containing protein -
PJH08_RS07555 (PJH08_07555) 1736263..1737111 + 849 WP_233885030.1 IS3 family transposase -
PJH08_RS07560 (PJH08_07560) 1737174..1737656 + 483 WP_239780262.1 toll/interleukin-1 receptor domain-containing protein -
PJH08_RS07565 (PJH08_07565) 1737669..1738214 + 546 WP_101955226.1 TIR domain-containing protein -
PJH08_RS07570 (PJH08_07570) 1738201..1738869 + 669 WP_101955225.1 hypothetical protein -
PJH08_RS07575 (PJH08_07575) 1739089..1739817 + 729 WP_271402617.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Uncharacterized protein HI1420

(8-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11762.92 Da        Isoelectric Point: 10.4596

>T268576 WP_271402616.1 NZ_CP116303:1734386-1734685 [Tenacibaculum finnmarkense]
MFFIEKTTEFDKWLKKLKDFKAKAKILFRIQKLESDEHFGDCKTVGDGIREMRINFAKGYRIYFKEKDGKIIILLIGGDK
STQQKDITKAKEIWKKLNK

Download         Length: 300 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10003.49 Da        Isoelectric Point: 4.7228

>AT268576 WP_101902711.1 NZ_CP116303:1734689-1734973 [Tenacibaculum finnmarkense]
MGTSRFEIADYLESKEMIAEYLNTVLEEGNNADVINAIGNIAKAIGMTKIAEETGLSRPSLYKALSDGAKPQFATIMKVL
KAIGGQIQVNPASA

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References