Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1694964..1695477 Replicon chromosome
Accession NZ_CP116303
Organism Tenacibaculum finnmarkense strain 20-4106-2

Toxin (Protein)


Gene name relE Uniprot ID A0A2H1YD11
Locus tag PJH08_RS07380 Protein ID WP_058885305.1
Coordinates 1695220..1695477 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2H1YCK0
Locus tag PJH08_RS07375 Protein ID WP_058885304.1
Coordinates 1694964..1695218 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJH08_RS07355 (PJH08_07355) 1690195..1690587 + 393 WP_101915088.1 helix-turn-helix domain-containing protein -
PJH08_RS07360 (PJH08_07360) 1690602..1691450 + 849 WP_233885030.1 IS3 family transposase -
PJH08_RS07365 (PJH08_07365) 1693459..1694019 + 561 WP_101902749.1 hypothetical protein -
PJH08_RS07370 (PJH08_07370) 1694568..1694855 - 288 WP_271402598.1 hypothetical protein -
PJH08_RS07375 (PJH08_07375) 1694964..1695218 + 255 WP_058885304.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PJH08_RS07380 (PJH08_07380) 1695220..1695477 + 258 WP_058885305.1 Txe/YoeB family addiction module toxin Toxin
PJH08_RS07385 (PJH08_07385) 1695657..1696715 + 1059 WP_232176506.1 nucleotidyltransferase domain-containing protein -
PJH08_RS07390 (PJH08_07390) 1696712..1697644 + 933 WP_271402599.1 nucleotide-binding protein -
PJH08_RS07395 (PJH08_07395) 1698629..1699285 + 657 WP_271402600.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10475.04 Da        Isoelectric Point: 9.7333

>T268575 WP_058885305.1 NZ_CP116303:1695220-1695477 [Tenacibaculum finnmarkense]
MKYTFVDESWEDYLYWQKTDKKKLKKINELLKDIARNPFDGIGKPEALKHKYAGFWSRRIDSEHRLIYQYREGEILIAKC
RFHYN

Download         Length: 258 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9677.10 Da        Isoelectric Point: 7.0115

>AT268575 WP_058885304.1 NZ_CP116303:1694964-1695218 [Tenacibaculum finnmarkense]
MQITTVSDFRKDIKSYLDRVIKDFETLIINRGKDSGIVVMSLQEYNSLMATNHELSSRKNELRLDSAIDKLKNGMTLNKD
LIEN

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2H1YD11

Antitoxin

Source ID Structure
AlphaFold DB A0A2H1YCK0

References