Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2875687..2875958 Replicon chromosome
Accession NZ_CP116044
Organism Escherichia coli strain STEC1575

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2875725..2875828 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2875687..2875958 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PHA55_RS14025 2872844..2874283 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
PHA55_RS14030 2874401..2874637 + 237 WP_001295499.1 YebV family protein -
PHA55_RS14035 2874742..2874933 + 192 WP_001296140.1 YebW family protein -
PHA55_RS14040 2874934..2875590 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2875687..2875958 + 272 - - Antitoxin
- 2875725..2875828 - 104 - - Toxin
PHA55_RS14045 2875986..2876327 - 342 WP_000976492.1 YebY family protein -
PHA55_RS14050 2876340..2877212 - 873 WP_000879285.1 copper homeostasis membrane protein CopD -
PHA55_RS14055 2877216..2877590 - 375 WP_000204699.1 CopC domain-containing protein YobA -
PHA55_RS14060 2877729..2877959 + 231 WP_000916763.1 DNA polymerase III subunit theta -
PHA55_RS14065 2878061..2878717 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
PHA55_RS14070 2878741..2879403 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T267711 NZ_CP116044:c2875828-2875725 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT267711 NZ_CP116044:2875687-2875958 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References