Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 1714528..1715050 Replicon chromosome
Accession NZ_CP116003
Organism Edwardsiella piscicida strain CC1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PED68_RS07900 Protein ID WP_069578568.1
Coordinates 1714528..1714809 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A411H7D8
Locus tag PED68_RS07905 Protein ID WP_069578569.1
Coordinates 1714799..1715050 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PED68_RS07885 (PED68_07885) 1709914..1710690 + 777 WP_073382315.1 hypothetical protein -
PED68_RS07890 (PED68_07890) 1710683..1712344 + 1662 WP_165362063.1 terminase -
PED68_RS07895 (PED68_07895) 1712341..1714455 + 2115 WP_129986139.1 portal protein -
PED68_RS07900 (PED68_07900) 1714528..1714809 - 282 WP_069578568.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PED68_RS07905 (PED68_07905) 1714799..1715050 - 252 WP_069578569.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PED68_RS07910 (PED68_07910) 1715328..1716329 + 1002 WP_129986135.1 hypothetical protein -
PED68_RS07915 (PED68_07915) 1716347..1717585 + 1239 WP_280977425.1 N4-gp56 family major capsid protein -
PED68_RS07920 (PED68_07920) 1717644..1718039 + 396 WP_080783446.1 hypothetical protein -
PED68_RS07925 (PED68_07925) 1718081..1718524 + 444 WP_080783445.1 hypothetical protein -
PED68_RS07930 (PED68_07930) 1718590..1719105 + 516 WP_236721582.1 hypothetical protein -
PED68_RS07935 (PED68_07935) 1719105..1719767 + 663 WP_109579934.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1676651..1738121 61470


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10738.62 Da        Isoelectric Point: 10.6993

>T267591 WP_069578568.1 NZ_CP116003:c1714809-1714528 [Edwardsiella piscicida]
MTYKLSFEKRALKEWKKLAPPIQSQLKKKLIERLENPHIPAARLSGRANRYKIKLRSSGYRLVYEVNDSEIILLVIAIGK
RADNDVYLAADGR

Download         Length: 282 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9154.26 Da        Isoelectric Point: 3.8074

>AT267591 WP_069578569.1 NZ_CP116003:c1715050-1714799 [Edwardsiella piscicida]
MAYQILTTTAASITDLKRNPMGTIAEGDGNAVAILNRNEPAFYCVPPELYAYYLELAENAALNRIADERLEDAEFVSVNI
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A411H7D8

References