Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 1663601..1664514 | Replicon | chromosome |
| Accession | NZ_CP115689 | ||
| Organism | Enterobacter hormaechei strain 2020CK-00204 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | PF325_RS07925 | Protein ID | WP_252051936.1 |
| Coordinates | 1663601..1664074 (-) | Length | 158 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | PF325_RS07930 | Protein ID | WP_023296216.1 |
| Coordinates | 1664071..1664514 (-) | Length | 148 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PF325_RS07910 (PF325_07910) | 1661031..1661471 | + | 441 | WP_271040651.1 | hypothetical protein | - |
| PF325_RS07915 (PF325_07915) | 1662660..1663133 | + | 474 | Protein_1536 | type I-F CRISPR-associated endonuclease Cas1f | - |
| PF325_RS07920 (PF325_07920) | 1663132..1663578 | + | 447 | Protein_1537 | type I-F CRISPR-associated endoribonuclease Cas6/Csy4 | - |
| PF325_RS07925 (PF325_07925) | 1663601..1664074 | - | 474 | WP_252051936.1 | RES domain-containing protein | Toxin |
| PF325_RS07930 (PF325_07930) | 1664071..1664514 | - | 444 | WP_023296216.1 | DUF2384 domain-containing protein | Antitoxin |
| PF325_RS07940 (PF325_07940) | 1667680..1667898 | - | 219 | WP_002211347.1 | translation initiation factor IF-1 | - |
| PF325_RS07945 (PF325_07945) | 1668183..1668887 | - | 705 | WP_232959876.1 | leucyl/phenylalanyl-tRNA--protein transferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 1655942..1704913 | 48971 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 158 a.a. Molecular weight: 17568.95 Da Isoelectric Point: 5.5052
>T267268 WP_252051936.1 NZ_CP115689:c1664074-1663601 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFHKALNSVELMPFNFDTRLAEKTAP
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFHKALNSVELMPFNFDTRLAEKTAP
Download Length: 474 bp
Antitoxin
Download Length: 148 a.a. Molecular weight: 16512.81 Da Isoelectric Point: 6.4819
>AT267268 WP_023296216.1 NZ_CP115689:c1664514-1664071 [Enterobacter hormaechei]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA
Download Length: 444 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|