Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-stbD/ParE(toxin)
Location 2605859..2606429 Replicon chromosome
Accession NZ_CP114976
Organism Denitrificimonas caeni strain CE14

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag O6P33_RS12140 Protein ID WP_269818035.1
Coordinates 2605859..2606140 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID -
Locus tag O6P33_RS12145 Protein ID WP_269818036.1
Coordinates 2606142..2606429 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O6P33_RS12120 (O6P33_12120) 2601694..2602650 - 957 WP_269819529.1 signal peptide peptidase SppA -
O6P33_RS12125 (O6P33_12125) 2602743..2603423 - 681 WP_269818032.1 HAD-IA family hydrolase -
O6P33_RS12130 (O6P33_12130) 2603505..2604641 - 1137 WP_269818033.1 Do family serine endopeptidase AlgW -
O6P33_RS12135 (O6P33_12135) 2604835..2605593 + 759 WP_269818034.1 Nif3-like dinuclear metal center hexameric protein -
O6P33_RS12140 (O6P33_12140) 2605859..2606140 - 282 WP_269818035.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O6P33_RS12145 (O6P33_12145) 2606142..2606429 - 288 WP_269818036.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O6P33_RS12150 (O6P33_12150) 2607389..2608306 + 918 WP_269818037.1 sulfate adenylyltransferase subunit CysD -
O6P33_RS12155 (O6P33_12155) 2608319..2610214 + 1896 WP_269818038.1 sulfate adenylyltransferase subunit CysN -
O6P33_RS12160 (O6P33_12160) 2610370..2611293 - 924 WP_269818039.1 ChaN family lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11025.13 Da        Isoelectric Point: 11.0986

>T267045 WP_269818035.1 NZ_CP114976:c2606140-2605859 [Denitrificimonas caeni]
MYQLGFGRQARKEWDKLSKPIQLQFALKLKERLKNPHVKKDALSGMPHCYKIKLRSIGFRLVYQVLDQTLVITVVAVGKR
ERNEVYRKARERL

Download         Length: 282 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10496.10 Da        Isoelectric Point: 4.0061

>AT267045 WP_269818036.1 NZ_CP114976:c2606429-2606142 [Denitrificimonas caeni]
MNMVQLTPLLADLSASVTELKKDPMGIIRSGLGETVVILNRNEPAFYAVPPAQYELMMQLIDDAHLAQLVKQRQDDPVEM
VDIDDLIQQASSISS

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References