Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1439070..1439727 Replicon chromosome
Accession NZ_CP114796
Organism Providencia sp. 21OH12SH02B-Prov

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag O7C57_RS06825 Protein ID WP_163860914.1
Coordinates 1439317..1439727 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag O7C57_RS06820 Protein ID WP_154624313.1
Coordinates 1439070..1439336 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O7C57_RS06805 (O7C57_06805) 1434222..1437098 + 2877 WP_269723798.1 aminomethyl-transferring glycine dehydrogenase -
O7C57_RS06810 (O7C57_06810) 1437195..1437815 - 621 WP_154624315.1 HD domain-containing protein -
O7C57_RS06815 (O7C57_06815) 1437827..1438816 - 990 WP_154624314.1 tRNA-modifying protein YgfZ -
O7C57_RS06820 (O7C57_06820) 1439070..1439336 + 267 WP_154624313.1 FAD assembly factor SdhE Antitoxin
O7C57_RS06825 (O7C57_06825) 1439317..1439727 + 411 WP_163860914.1 protein YgfX Toxin
O7C57_RS06830 (O7C57_06830) 1439772..1440290 - 519 WP_154624312.1 flavodoxin FldB -
O7C57_RS06835 (O7C57_06835) 1440375..1441298 + 924 WP_154624329.1 site-specific tyrosine recombinase XerD -
O7C57_RS06840 (O7C57_06840) 1441318..1442019 + 702 WP_154624311.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
O7C57_RS06845 (O7C57_06845) 1442029..1443762 + 1734 WP_196713356.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15375.24 Da        Isoelectric Point: 10.8779

>T266839 WP_163860914.1 NZ_CP114796:1439317-1439727 [Providencia sp. 21OH12SH02B-Prov]
VVLWKSNLSISWKTQLFSTCAHGLVGFILLVAPWAPGNSMVWLPLLAIVIASWAKSQKSISKIKGTAVLVNGNKVQWKKN
EWNIIKQPWCSRVGILLTLSALQGKQQKIRLWIAKDALSEESWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10578.07 Da        Isoelectric Point: 4.7132

>AT266839 WP_154624313.1 NZ_CP114796:1439070-1439336 [Providencia sp. 21OH12SH02B-Prov]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDSLSDKDKQTFVRLLECADPDLFNWLMNHGRPDDEELFGMVKLIQERN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References