Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 4838514..4839772 | Replicon | chromosome |
Accession | NZ_CP114761 | ||
Organism | Pseudomonas aeruginosa strain NF143349 |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | O4M85_RS22620 | Protein ID | WP_019725936.1 |
Coordinates | 4838514..4839269 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | O4M85_RS22625 | Protein ID | WP_003086329.1 |
Coordinates | 4839404..4839772 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
O4M85_RS22610 (O4M85_22610) | 4833686..4836229 | + | 2544 | WP_003112526.1 | acyl-homoserine-lactone acylase QuiP | - |
O4M85_RS22615 (O4M85_22615) | 4836384..4837745 | - | 1362 | WP_003081943.1 | DNA recombination protein RmuC | - |
O4M85_RS22620 (O4M85_22620) | 4838514..4839269 | - | 756 | WP_019725936.1 | RES family NAD+ phosphorylase | Toxin |
O4M85_RS22625 (O4M85_22625) | 4839404..4839772 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
O4M85_RS22630 (O4M85_22630) | 4839845..4841131 | - | 1287 | WP_003163134.1 | FAD-binding oxidoreductase | - |
O4M85_RS22635 (O4M85_22635) | 4841187..4842776 | - | 1590 | WP_019725935.1 | aldehyde dehydrogenase family protein | - |
O4M85_RS22640 (O4M85_22640) | 4842855..4843331 | + | 477 | WP_019725934.1 | hypothetical protein | - |
O4M85_RS22645 (O4M85_22645) | 4843334..4843609 | - | 276 | WP_010792073.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28192.33 Da Isoelectric Point: 8.0554
>T266801 WP_019725936.1 NZ_CP114761:c4839269-4838514 [Pseudomonas aeruginosa]
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSGHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSGHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT266801 WP_003086329.1 NZ_CP114761:c4839772-4839404 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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