Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 5418..5928 Replicon plasmid unnamed1
Accession NZ_CP114518
Organism Ligilactobacillus salivarius strain S91

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U05_RS00035 Protein ID WP_044006010.1
Coordinates 5418..5669 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U05_RS00040 Protein ID WP_044006009.1
Coordinates 5662..5928 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U05_RS00015 (O2U05_00015) 740..1591 - 852 WP_283475147.1 hypothetical protein -
O2U05_RS00020 (O2U05_00020) 2037..2435 - 399 WP_087250758.1 hypothetical protein -
O2U05_RS00025 (O2U05_00025) 2444..3541 - 1098 WP_044006012.1 ParM/StbA family protein -
O2U05_RS00030 (O2U05_00030) 3856..4962 + 1107 WP_283475109.1 hypothetical protein -
O2U05_RS00035 (O2U05_00035) 5418..5669 - 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U05_RS00040 (O2U05_00040) 5662..5928 - 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U05_RS00045 (O2U05_00045) 6023..6358 - 336 WP_283475111.1 hypothetical protein -
O2U05_RS00050 (O2U05_00050) 7278..7613 - 336 WP_283475113.1 hypothetical protein -
O2U05_RS00055 (O2U05_00055) 7760..8146 - 387 WP_283475114.1 hypothetical protein -
O2U05_RS00060 (O2U05_00060) 8250..8663 - 414 WP_283475116.1 hypothetical protein -
O2U05_RS00065 (O2U05_00065) 8840..10015 - 1176 WP_283558376.1 RepB family plasmid replication initiator protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..144347 144347


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266668 WP_044006010.1 NZ_CP114518:c5669-5418 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266668 WP_044006009.1 NZ_CP114518:c5928-5662 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References