Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 12115..12625 Replicon plasmid unnamed2
Accession NZ_CP114511
Organism Ligilactobacillus salivarius strain S35

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U02_RS10600 Protein ID WP_044006010.1
Coordinates 12115..12366 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U02_RS10605 Protein ID WP_044006009.1
Coordinates 12359..12625 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U02_RS10580 (O2U02_10585) 7437..8288 - 852 WP_283475147.1 hypothetical protein -
O2U02_RS10585 (O2U02_10590) 8734..9132 - 399 WP_087250758.1 hypothetical protein -
O2U02_RS10590 (O2U02_10595) 9141..10238 - 1098 WP_044006012.1 ParM/StbA family protein -
O2U02_RS10595 (O2U02_10600) 10553..11659 + 1107 WP_283475109.1 hypothetical protein -
O2U02_RS10600 (O2U02_10605) 12115..12366 - 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U02_RS10605 (O2U02_10610) 12359..12625 - 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U02_RS10610 (O2U02_10615) 12720..13055 - 336 WP_283475111.1 hypothetical protein -
O2U02_RS10615 (O2U02_10620) 13974..14309 - 336 WP_283475113.1 hypothetical protein -
O2U02_RS10620 (O2U02_10625) 14454..14813 - 360 WP_283475502.1 hypothetical protein -
O2U02_RS10625 (O2U02_10630) 14943..15356 - 414 WP_283475116.1 hypothetical protein -
O2U02_RS10630 (O2U02_10635) 15672..16662 - 991 Protein_15 RepB family plasmid replication initiator protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..124072 124072


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266665 WP_044006010.1 NZ_CP114511:c12366-12115 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266665 WP_044006009.1 NZ_CP114511:c12625-12359 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References