Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 455311..455964 Replicon chromosome
Accession NZ_CP114381
Organism Acinetobacter baumannii strain AB6870155

Toxin (Protein)


Gene name cptA Uniprot ID B0V6V2
Locus tag NH10_RS02195 Protein ID WP_000931890.1
Coordinates 455575..455964 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag NH10_RS02190 Protein ID WP_001288210.1
Coordinates 455311..455568 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NH10_RS02170 (NH10_000420) 450827..451834 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
NH10_RS02175 (NH10_000421) 451853..452230 + 378 WP_001216380.1 50S ribosomal protein L17 -
NH10_RS02180 (NH10_000422) 452411..453901 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
NH10_RS02185 (NH10_000423) 453951..455123 - 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
NH10_RS02190 (NH10_000424) 455311..455568 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
NH10_RS02195 (NH10_000425) 455575..455964 + 390 WP_000931890.1 membrane protein Toxin
NH10_RS02200 (NH10_000427) 456734..457819 + 1086 WP_000049106.1 hypothetical protein -
NH10_RS02205 (NH10_000428) 457897..458463 + 567 WP_000651536.1 rhombosortase -
NH10_RS02210 (NH10_000429) 458651..460846 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.98 Da        Isoelectric Point: 10.4623

>T266655 WP_000931890.1 NZ_CP114381:455575-455964 [Acinetobacter baumannii]
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT266655 WP_001288210.1 NZ_CP114381:455311-455568 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J1A4U0

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References