Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1970839..1970984 Replicon chromosome
Accession NZ_CP114375
Organism Klebsiella pneumoniae strain KP6870155

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1970875..1970977 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1970839..1970984 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOZ09_RS09750 1965969..1968029 + 2061 WP_004148850.1 oligopeptidase B -
NOZ09_RS09755 1968033..1968692 - 660 WP_002911407.1 exodeoxyribonuclease X -
NOZ09_RS09760 1968771..1969001 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NOZ09_RS09765 1969114..1969488 + 375 WP_023285314.1 CopC domain-containing protein YobA -
NOZ09_RS09770 1969492..1970361 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
NOZ09_RS09775 1970378..1970716 + 339 WP_002911404.1 YebY family protein -
- 1970839..1970984 - 146 - - Antitoxin
- 1970875..1970977 + 103 - - Toxin
NOZ09_RS09780 1971352..1971495 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NOZ09_RS09785 1971600..1972568 - 969 WP_004151446.1 VirK/YbjX family protein -
NOZ09_RS09790 1972725..1973378 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
NOZ09_RS09795 1973375..1973566 - 192 WP_002911395.1 YebW family protein -
NOZ09_RS09800 1973664..1973903 - 240 WP_002911393.1 YebV family protein -
NOZ09_RS09805 1974019..1975452 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T266644 NZ_CP114375:1970875-1970977 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT266644 NZ_CP114375:c1970984-1970839 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References