Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2643120..2643820 Replicon chromosome
Accession NZ_CP114115
Organism Pseudomonas sp. GXZC

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag OZ428_RS12665 Protein ID WP_269133558.1
Coordinates 2643120..2643416 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag OZ428_RS12670 Protein ID WP_269133559.1
Coordinates 2643419..2643820 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ428_RS12640 (OZ428_12640) 2638264..2638503 - 240 WP_033902121.1 DNA-binding protein -
OZ428_RS12645 (OZ428_12645) 2638586..2638951 + 366 WP_177003196.1 helix-turn-helix transcriptional regulator -
OZ428_RS12650 (OZ428_12650) 2639103..2639744 + 642 WP_016977368.1 UvrY/SirA/GacA family response regulator transcription factor -
OZ428_RS12655 (OZ428_12655) 2639746..2641569 + 1824 WP_269133556.1 excinuclease ABC subunit UvrC -
OZ428_RS12660 (OZ428_12660) 2641623..2643110 + 1488 WP_269133557.1 site-specific integrase -
OZ428_RS12665 (OZ428_12665) 2643120..2643416 + 297 WP_269133558.1 type II toxin-antitoxin system MqsR family toxin Toxin
OZ428_RS12670 (OZ428_12670) 2643419..2643820 + 402 WP_269133559.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
OZ428_RS12675 (OZ428_12675) 2644377..2644718 + 342 WP_269133560.1 hypothetical protein -
OZ428_RS12680 (OZ428_12680) 2644899..2645126 + 228 WP_269133561.1 hypothetical protein -
OZ428_RS12685 (OZ428_12685) 2645469..2646134 + 666 WP_269133562.1 hypothetical protein -
OZ428_RS12690 (OZ428_12690) 2646134..2646835 + 702 WP_269133563.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2637520..2681820 44300


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11016.86 Da        Isoelectric Point: 8.0410

>T266256 WP_269133558.1 NZ_CP114115:2643120-2643416 [Pseudomonas sp. GXZC]
MEKKTPHCKLTTVKALIESGKVRTTNSARVGADALNLDLSDMLAVVMGLQPMDFYKSMTTYADHTIWQDVYRPHTKAGNV
YLKLTVIEDVLIVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14789.03 Da        Isoelectric Point: 8.1192

>AT266256 WP_269133559.1 NZ_CP114115:2643419-2643820 [Pseudomonas sp. GXZC]
MKCPVCGAAGLVHDTRDVPYTYKGETTLIKNVTGDFCPSCSESVLDLTESDRVMKEMRAFSKRTNADLVDPGYITKVRKK
LDLDQREAAEIFGGGVNAFSRYENGKTKPPLALIKLLKVLDRHPELLNEVRTA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References