Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4860073..4860589 Replicon chromosome
Accession NZ_CP114035
Organism Pseudomonas putida strain GMI12077

Toxin (Protein)


Gene name relE Uniprot ID A0A8I0ZDP4
Locus tag OZ911_RS22270 Protein ID WP_023047836.1
Coordinates 4860073..4860360 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1L7NIA2
Locus tag OZ911_RS22275 Protein ID WP_023047837.1
Coordinates 4860350..4860589 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ911_RS22250 (OZ911_22250) 4856360..4856494 + 135 WP_023048542.1 hypothetical protein -
OZ911_RS22255 (OZ911_22255) 4857000..4858250 + 1251 WP_016488688.1 ribonucleotide-diphosphate reductase subunit beta -
OZ911_RS22260 (OZ911_22260) 4858337..4858810 - 474 WP_134792775.1 hypothetical protein -
OZ911_RS22265 (OZ911_22265) 4859235..4859771 + 537 WP_023047835.1 Bro-N domain-containing protein -
OZ911_RS22270 (OZ911_22270) 4860073..4860360 - 288 WP_023047836.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OZ911_RS22275 (OZ911_22275) 4860350..4860589 - 240 WP_023047837.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZ911_RS22280 (OZ911_22280) 4861309..4862547 + 1239 WP_004577198.1 OprD family porin -
OZ911_RS22285 (OZ911_22285) 4862786..4863592 + 807 WP_023047838.1 NAD(P)-dependent oxidoreductase -
OZ911_RS22290 (OZ911_22290) 4863618..4864499 + 882 WP_016488690.1 SMP-30/gluconolactonase/LRE family protein -
OZ911_RS22295 (OZ911_22295) 4864564..4865535 + 972 WP_016488691.1 TRAP transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11242.07 Da        Isoelectric Point: 10.1560

>T266220 WP_023047836.1 NZ_CP114035:c4860360-4860073 [Pseudomonas putida]
MTYSLDFDARALKEWKKLGDTVRQQFKKKLAEVLLNPRIEANRLHSLPDCYKIKLRSSGFRLVYQVIDQEVVVFVVAVDR
RERDQAYKKAAERLE

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9085.43 Da        Isoelectric Point: 4.6310

>AT266220 WP_023047837.1 NZ_CP114035:c4860589-4860350 [Pseudomonas putida]
MASINIRVDDDLKARAYKELERLGVTPSELMRQALQYVAERGKLPFRPVLMTEEDEDLIATVQERLASAQRVRVQLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1L7NIA2

References