Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 24450..24974 Replicon chromosome
Accession NZ_CP114029
Organism Jiella sp. HL-NP1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag OH818_RS01205 Protein ID WP_268881423.1
Coordinates 24450..24722 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OH818_RS01210 Protein ID WP_268881424.1
Coordinates 24735..24974 (-) Length 80 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH818_RS01190 (OH818_01190) 19466..21966 - 2501 Protein_12 ATP-dependent helicase HrpB -
OH818_RS01195 (OH818_01195) 21963..22739 - 777 WP_268881421.1 ATP-binding cassette domain-containing protein -
OH818_RS01200 (OH818_01200) 22736..24460 - 1725 WP_268881422.1 ABC transporter permease subunit -
OH818_RS01205 (OH818_01205) 24450..24722 - 273 WP_268881423.1 Txe/YoeB family addiction module toxin Toxin
OH818_RS01210 (OH818_01210) 24735..24974 - 240 WP_268881424.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OH818_RS01215 (OH818_01215) 25130..26344 - 1215 WP_268881425.1 ABC transporter substrate-binding protein -
OH818_RS01220 (OH818_01220) 26556..27300 + 745 Protein_18 SDR family NAD(P)-dependent oxidoreductase -
OH818_RS01225 (OH818_01225) 27338..27988 - 651 WP_268881426.1 hypothetical protein -
OH818_RS01230 (OH818_01230) 27991..28635 - 645 WP_268881427.1 HdeD family acid-resistance protein -
OH818_RS01235 (OH818_01235) 28732..29316 - 585 WP_268881428.1 NADPH-dependent FMN reductase -
OH818_RS01240 (OH818_01240) 29313..29930 - 618 WP_268881429.1 rRNA adenine N-6-methyltransferase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-88)

Antitoxin

(1-60)


Sequences


Toxin        


Download         Length: 91 a.a.        Molecular weight: 10635.14 Da        Isoelectric Point: 10.8843

>T266211 WP_268881423.1 NZ_CP114029:c24722-24450 [Jiella sp. HL-NP1]
VRVQFTPRAWLDYQHWIEADRALLTRLNALIAEARRSPFVGTGKPEPLRGEFSGWWSRRIDREHRLVYRVNGKGEEQTLV
IAACRFHYGR

Download         Length: 273 bp


Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9012.26 Da        Isoelectric Point: 7.9242

>AT266211 WP_268881424.1 NZ_CP114029:c24974-24735 [Jiella sp. HL-NP1]
MPHVSFSELRANMASHFDRIEADRTELIVTRQNHEPVVVLALSEWEAIQETMHLLRLTGQCRTSSPIDRAGRCRRGGRA

Download         Length: 240 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References