Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 36254..36785 Replicon plasmid paaa
Accession NZ_CP113828
Organism Pandoraea sp. XJJ-1

Toxin (Protein)


Gene name relE Uniprot ID I2ALI9
Locus tag OYT13_RS25035 Protein ID WP_011114071.1
Coordinates 36254..36535 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID I2ALI8
Locus tag OYT13_RS25040 Protein ID WP_011114070.1
Coordinates 36522..36785 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OYT13_RS25025 (OYT13_25025) 31833..32102 + 270 WP_268567935.1 hypothetical protein -
OYT13_RS25030 (OYT13_25030) 32217..35132 + 2916 WP_003049965.1 Tn3-like element IS1071 family transposase -
OYT13_RS25035 (OYT13_25035) 36254..36535 - 282 WP_011114071.1 type II toxin-antitoxin system YafQ family toxin Toxin
OYT13_RS25040 (OYT13_25040) 36522..36785 - 264 WP_011114070.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OYT13_RS25045 (OYT13_25045) 36958..37386 + 429 WP_011114069.1 antirestriction protein -
OYT13_RS25050 (OYT13_25050) 37431..37649 + 219 WP_012478187.1 hypothetical protein -
OYT13_RS25055 (OYT13_25055) 37661..38869 + 1209 WP_011114068.1 hypothetical protein -
OYT13_RS25060 (OYT13_25060) 38886..39143 + 258 WP_011114067.1 transcriptional repressor KorC -
OYT13_RS25065 (OYT13_25065) 39301..39537 + 237 WP_011114066.1 stable inheritance protein KleA -
OYT13_RS25070 (OYT13_25070) 39746..40072 + 327 WP_011114065.1 KleE stable inheritance protein -
OYT13_RS25075 (OYT13_25075) 40074..40403 + 330 WP_011114064.1 DUF2761 domain-containing protein -
OYT13_RS25080 (OYT13_25080) 40510..40818 + 309 WP_011114062.1 transcriptional regulator KorA -
OYT13_RS25085 (OYT13_25085) 40815..41579 + 765 WP_011114061.1 ParA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..51847 51847


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-83)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10743.19 Da        Isoelectric Point: 7.4750

>T266078 WP_011114071.1 NZ_CP113828:c36535-36254 [Pandoraea sp. XJJ-1]
MRQIERTGQFKRDYKREAKGQHRATLDADLVPVLVALADDQPLEPRHRDHALTGDWKDHRDCHVKPDLVLIYQKPDADTL
RLVRLGSHSELGL

Download         Length: 282 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9255.82 Da        Isoelectric Point: 5.7905

>AT266078 WP_011114070.1 NZ_CP113828:c36785-36522 [Pandoraea sp. XJJ-1]
MAANQLVQTRIDGAIKEEAAAVLAAMGLTVSDAVRLLLTKVAQDKALPFEPLIPNATTIEAMKEARKGKLPRFATVNDLM
ADLHAAD

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1U9V4I5

Antitoxin

Source ID Structure
AlphaFold DB A0A1U9V3I2

References