Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1130831..1132688 Replicon chromosome
Accession NZ_CP113827
Organism Pandoraea sp. XJJ-1

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag OYT13_RS05220 Protein ID WP_268567366.1
Coordinates 1130831..1131739 (+) Length 303 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID A0A9E9ID32
Locus tag OYT13_RS05225 Protein ID WP_026132232.1
Coordinates 1131819..1132688 (+) Length 290 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OYT13_RS05195 (OYT13_05195) 1126240..1127316 + 1077 WP_174975102.1 porin -
OYT13_RS05200 (OYT13_05200) 1127630..1128499 + 870 WP_017235321.1 ABC transporter ATP-binding protein -
OYT13_RS05205 (OYT13_05205) 1128539..1129321 + 783 WP_017235322.1 ABC transporter permease -
OYT13_RS05210 (OYT13_05210) 1129340..1130131 + 792 WP_268567365.1 SDR family oxidoreductase -
OYT13_RS05215 (OYT13_05215) 1130172..1130729 + 558 WP_017235324.1 cupin domain-containing protein -
OYT13_RS05220 (OYT13_05220) 1130831..1131739 + 909 WP_268567366.1 alpha/beta hydrolase Toxin
OYT13_RS05225 (OYT13_05225) 1131819..1132688 + 870 WP_026132232.1 IclR family transcriptional regulator Antitoxin
OYT13_RS05230 (OYT13_05230) 1132685..1133491 + 807 WP_268567367.1 SDR family oxidoreductase -
OYT13_RS05235 (OYT13_05235) 1133484..1135136 + 1653 WP_017235328.1 thiamine pyrophosphate-binding protein -
OYT13_RS05240 (OYT13_05240) 1135129..1135947 + 819 WP_017235329.1 aspartate dehydrogenase -
OYT13_RS05245 (OYT13_05245) 1135961..1137457 + 1497 WP_017235330.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(53-288)

Antitoxin

Transcription regulator IclR, C-terminal

(144-267)


Sequences

Toxin        


Download         Length: 303 a.a.        Molecular weight: 31165.35 Da        Isoelectric Point: 5.9322

>T266074 WP_268567366.1 NZ_CP113827:1130831-1131739 [Pandoraea sp. XJJ-1]
MQAEAFQSEVPEDAAVAPLCARLDAFPYRTVATRVGTVGYRSAGTQAEGAMPVVMLHGIGSGAASWLAQFEATNLHAALY
AWDAPGYGQTTNVADAEPHADAYAEALAAWLDALGLTRVALVGHSLGAIMATQFASRAPQRVSGLFLCSPAGGYGKADAQ
VRLSKRDGRLAMLDKLGPTGMARERSDNLVAPNAAALPRAWVKWNMARVLPAGYRQATHLLSNGDVAGALAQYVAANAGP
VAVAVGTQDAVTPPAACQAIAEAAGVPLQIIEGAGHASYIETPDVLNAALAAWLERIAAGER

Download         Length: 909 bp

Antitoxin


Download         Length: 290 a.a.        Molecular weight: 31628.14 Da        Isoelectric Point: 6.3597

>AT266074 WP_026132232.1 NZ_CP113827:1131819-1132688 [Pandoraea sp. XJJ-1]
MQGEGESEDLVDGAATETRYLVPGLERGLRILTQFSPREPVFSAPELSQRLGIPRTTVFRLLQTLEAMGFLERAGGEKNF
RLGVAVLRLGFEYLSSLELTDLGIPIIERLRDATQLTSHIVIRDGRDIVFVAKAQSVASVFNSIKVNVGTRLPAHATVHG
HVLMGDLTLAELRALYPEKTLEKYTPQTPETITELFERVREDAERGYAVSASSFERGISVVSAPVRNDAGRICAAITVTI
PRATLDASVLDAGLIAQVREAADALSHRLNYRPGSDDRATPYMKSLGLK

Download         Length: 870 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References