Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 2490492..2491033 Replicon chromosome
Accession NZ_CP113797
Organism Leptolyngbya sp. PKUAC-SCTA174

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OXH18_RS10755 Protein ID WP_268612782.1
Coordinates 2490492..2490812 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OXH18_RS10760 Protein ID WP_268612783.1
Coordinates 2490809..2491033 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXH18_RS10750 (OXH18_10750) 2486468..2490352 + 3885 WP_268612781.1 hypothetical protein -
OXH18_RS10755 (OXH18_10755) 2490492..2490812 - 321 WP_268612782.1 DUF5615 family PIN-like protein Toxin
OXH18_RS10760 (OXH18_10760) 2490809..2491033 - 225 WP_268612783.1 DUF433 domain-containing protein Antitoxin
OXH18_RS10765 (OXH18_10765) 2491061..2491279 - 219 WP_268612784.1 hypothetical protein -
OXH18_RS10770 (OXH18_10770) 2491284..2491412 - 129 WP_268612785.1 hypothetical protein -
OXH18_RS10775 (OXH18_10775) 2491762..2492916 + 1155 WP_268612786.1 XdhC/CoxI family protein -
OXH18_RS10780 (OXH18_10780) 2492999..2493649 + 651 WP_268612787.1 nucleotidyltransferase family protein -
OXH18_RS10785 (OXH18_10785) 2493616..2494662 - 1047 WP_268612788.1 DUF3616 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(4-79)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11712.45 Da        Isoelectric Point: 4.3184

>T266063 WP_268612782.1 NZ_CP113797:c2490812-2490492 [Leptolyngbya sp. PKUAC-SCTA174]
MTTIWIDAHLSPAIATWITDTFGITALALRDLSLRDAEDPEIFEAAKAQGIIFMTKDSDFVDLVERLGSPPQIIWLTCGN
TSNARLREILSAVLPETLKLLRSGEN

Download         Length: 321 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8248.65 Da        Isoelectric Point: 5.7855

>AT266063 WP_268612783.1 NZ_CP113797:c2491033-2490809 [Leptolyngbya sp. PKUAC-SCTA174]
MSKLLERITVNPRQCGGRPCIRGMRIRVSDVLDLFAAGLSAEEILEDLPDLEMDDIRASLTYAARKLNHPILVA

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References