Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4031557..4032073 Replicon chromosome
Accession NZ_CP113537
Organism Salmonella enterica strain YZY

Toxin (Protein)


Gene name relE Uniprot ID A0A3V5VNJ7
Locus tag OXV04_RS19265 Protein ID WP_000220577.1
Coordinates 4031557..4031841 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V7ISI8
Locus tag OXV04_RS19270 Protein ID WP_000212724.1
Coordinates 4031831..4032073 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV04_RS19250 (4026769) 4026769..4028421 + 1653 WP_126524329.1 alpha,alpha-phosphotrehalase -
OXV04_RS19255 (4028830) 4028830..4030968 + 2139 WP_000187818.1 anaerobic ribonucleoside-triphosphate reductase -
OXV04_RS19260 (4031089) 4031089..4031553 + 465 WP_031605772.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
OXV04_RS19265 (4031557) 4031557..4031841 - 285 WP_000220577.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OXV04_RS19270 (4031831) 4031831..4032073 - 243 WP_000212724.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OXV04_RS19275 (4032151) 4032151..4034064 - 1914 WP_140902122.1 BglG family transcription antiterminator -
OXV04_RS19280 (4034081) 4034081..4034821 - 741 WP_126524331.1 KDGP aldolase family protein -
OXV04_RS19285 (4034818) 4034818..4035936 - 1119 WP_126524332.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
OXV04_RS19290 (4035920) 4035920..4037053 - 1134 WP_126524333.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10912.71 Da        Isoelectric Point: 9.8739

>T265947 WP_000220577.1 NZ_CP113537:c4031841-4031557 [Salmonella enterica]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARLNDLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT265947 WP_000212724.1 NZ_CP113537:c4032073-4031831 [Salmonella enterica]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V5VNJ7

Antitoxin

Source ID Structure
AlphaFold DB A0A5H5JRI5

References