Detailed information of TA system TA265891

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 3550711..3551114
• Replicon: chromosome
• Accession: NZ_CP113534
• Organism: Salmonella enterica strain ZYX

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: OXV08_RS17220
• Protein ID: WP_023209683.1
• Coordinates: 3550986..3551114 (+)
• Length: 43 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3550711..3551064 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OXV08_RS17185	3545983..3546477	-	495	WP_000839695.1	Saf-pilin pilus formation protein SafA	-
OXV08_RS17190	3547238..3547942	-	705	Protein_3363	integrase core domain-containing protein	-
OXV08_RS17195	3547995..3548309	+	315	WP_011233128.1	SymE family type I addiction module toxin	-
OXV08_RS17200	3548376..3548654	-	279	WP_012543321.1	hypothetical protein	-
OXV08_RS17205	3548962..3549429	-	468	WP_001674144.1	hypothetical protein	-
OXV08_RS17210	3549426..3549743	-	318	WP_153274541.1	hypothetical protein	-
OXV08_RS17215	3550301..3550534	-	234	WP_125541564.1	hypothetical protein	-
-	3550711..3551064	-	354	-	-	Antitoxin
OXV08_RS17220	3550986..3551114	+	129	WP_023209683.1	hypothetical protein	Toxin
OXV08_RS17225	3551197..3551517	-	321	WP_223201872.1	Imm8 family immunity protein	-
OXV08_RS17230	3552297..3552662	-	366	WP_001231281.1	hypothetical protein	-
OXV08_RS17235	3552628..3555429	-	2802	WP_000449788.1	RHS repeat-associated core domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3530399..3571537	41138

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 43 a.a.
• Molecular weight: 4492.16 Da
• Isoelectric Point: 4.4551

>T265891 WP_023209683.1 NZ_CP113534:3550986-3551114 [Salmonella enterica]
VKISDGCIVLMADGNEVQELREQLYQAKRVVKGGEGCAGLVD

Nucleotide

• Length: 129 bp

Antitoxin

Nucleotide

• Length: 354 bp

>AT265891 NZ_CP113534:c3551064-3550711 [Salmonella enterica]
CCTGATAAAGCTGTTCGCGCAGCTCCTGCACCTCGTTACCGTCCGCCATTAGCACAATACACCCGTCCGAAATCTTCACC
GTCACGCCGCTCCCCGGTCTCAAATCCCGCTTCTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGC
AGGTTTCGCTGTTGATGTGGCGTACGCTGGCGCCGGAGGTATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCC
GGATGCTGGCTGATTGTGGAGCTCAGGGTGAGTGAGTATGGGCGCGACATCTTGGCACCGCGCCCCCCCTCTCCCCGGCC
AGTGATGAGCAACCGGCTACCGGGGCCGTATTTT

Structures

Antitoxin