Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelB-YoeB
Location 3150776..3151281 Replicon chromosome
Accession NZ_CP113517
Organism Methylomonas rapida strain MP1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NM686_RS14895 Protein ID WP_255188644.1
Coordinates 3150776..3151030 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NM686_RS14900 Protein ID WP_255188645.1
Coordinates 3151027..3151281 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NM686_RS14875 (NM686_014875) 3146904..3147281 + 378 WP_255188640.1 type III-A CRISPR-associated protein Csm2 -
NM686_RS14880 (NM686_014880) 3147297..3148088 + 792 WP_255188641.1 type III-A CRISPR-associated RAMP protein Csm3 -
NM686_RS14885 (NM686_014885) 3148090..3149046 + 957 WP_255188642.1 type III-A CRISPR-associated RAMP protein Csm4 -
NM686_RS14890 (NM686_014890) 3149132..3150541 + 1410 WP_255188643.1 type III-A CRISPR-associated RAMP protein Csm5 -
NM686_RS14895 (NM686_014895) 3150776..3151030 + 255 WP_255188644.1 type II toxin-antitoxin system prevent-host-death family antitoxin Toxin
NM686_RS14900 (NM686_014900) 3151027..3151281 + 255 WP_255188645.1 Txe/YoeB family addiction module toxin Antitoxin
NM686_RS14905 (NM686_014905) 3151347..3152612 + 1266 WP_255188646.1 TIGR02710 family CRISPR-associated CARF protein -
NM686_RS14910 (NM686_014910) 3152629..3153165 + 537 WP_255188647.1 transposase -
NM686_RS14915 (NM686_014915) 3153211..3155295 + 2085 WP_255188648.1 CRISPR-associated ring nuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)

Antitoxin

Toxin YoeB

(5-84)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9339.43 Da        Isoelectric Point: 4.3444

>T265867 WP_255188644.1 NZ_CP113517:3150776-3151030 [Methylomonas rapida]
MDTINYTTLRNNLASVLDKVNDDHNPVLVTRQNGKPAVILSLEDYKSFEETAYLMASPVNAQRLNQAIAEVEAGNTVNHE
LIEP

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 10171.64 Da        Isoelectric Point: 9.3600

>AT265867 WP_255188645.1 NZ_CP113517:3151027-3151281 [Methylomonas rapida]
MILAWATNAWDDYLYWQATDKKVLKRINTLIEDIKRQPFTGIGDPELLKHNWSGYWSRRIDREHRLVYKADATTITIVQC
RYHY

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References