Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3768197..3768761 Replicon chromosome
Accession NZ_CP112867
Organism Pseudomonas quebecensis isolate S1Bt7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OSC48_RS17200 Protein ID WP_266246111.1
Coordinates 3768474..3768761 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OSC48_RS17195 Protein ID WP_181081261.1
Coordinates 3768197..3768484 (+) Length 96 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSC48_RS17160 (OSC48_17160) 3763309..3764088 - 780 WP_181081266.1 amino acid ABC transporter ATP-binding protein -
OSC48_RS17165 (OSC48_17165) 3764091..3764867 - 777 WP_266246104.1 amino acid ABC transporter permease -
OSC48_RS17170 (OSC48_17170) 3764879..3765685 - 807 WP_266246106.1 ABC transporter substrate-binding protein -
OSC48_RS17175 (OSC48_17175) 3765747..3766415 - 669 WP_253508486.1 GntR family transcriptional regulator -
OSC48_RS17180 (OSC48_17180) 3766499..3766807 - 309 WP_266246108.1 hypothetical protein -
OSC48_RS17185 (OSC48_17185) 3767006..3767431 + 426 WP_253508488.1 hypothetical protein -
OSC48_RS17190 (OSC48_17190) 3767483..3767800 - 318 WP_034099046.1 transcriptional regulator -
OSC48_RS17195 (OSC48_17195) 3768197..3768484 + 288 WP_181081261.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OSC48_RS17200 (OSC48_17200) 3768474..3768761 + 288 WP_266246111.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OSC48_RS17205 (OSC48_17205) 3768800..3769576 - 777 WP_266246113.1 DUF1828 domain-containing protein -
OSC48_RS17210 (OSC48_17210) 3769576..3770091 - 516 WP_266246114.1 hypothetical protein -
OSC48_RS17215 (OSC48_17215) 3770136..3770372 - 237 WP_266246115.1 hypothetical protein -
OSC48_RS17220 (OSC48_17220) 3770628..3770849 + 222 WP_266246116.1 hypothetical protein -
OSC48_RS17225 (OSC48_17225) 3770899..3771123 + 225 WP_266246118.1 Arc family DNA-binding protein -
OSC48_RS17230 (OSC48_17230) 3771120..3771287 + 168 WP_266246119.1 hypothetical protein -
OSC48_RS17235 (OSC48_17235) 3771280..3771627 + 348 WP_266246121.1 hypothetical protein -
OSC48_RS17240 (OSC48_17240) 3771920..3773104 + 1185 WP_266246122.1 tyrosine-type recombinase/integrase -
OSC48_RS17250 (OSC48_17250) 3773354..3773710 - 357 WP_003174972.1 MerR family transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 96 a.a.        Molecular weight: 10987.84 Da        Isoelectric Point: 10.2255

>T264895 WP_266246111.1 NZ_CP112867:3768474-3768761 [Pseudomonas quebecensis]
MAAEYEVEWDPKALKELRKLDGTIRLQFLKKLQERQSGPRVPGDALHGMKDCYKIKLRGAGYRLVYRVEDERIVILVLAV
GKRERGSVYEQAGKR

Download         Length: 288 bp


Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10260.80 Da        Isoelectric Point: 4.4354

>AT264895 WP_181081261.1 NZ_CP112867:3768197-3768484 [Pseudomonas quebecensis]
MQNILADVAVSVSELKKNPSSVLSGANGMPVAVLNHNRVMGYMVPANVYEAMVERLDELELVQLVKARLDAKETPVRVSL
DDLIGEAEADIANGR

Download         Length: 288 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References