Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2080202..2080347 | Replicon | chromosome |
| Accession | NZ_CP110967 | ||
| Organism | Klebsiella pneumoniae subsp. pneumoniae strain LC-424/19 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2080238..2080340 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2080202..2080347 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NPX97_RS10220 (NPX97_10220) | 2075332..2077392 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| NPX97_RS10225 (NPX97_10225) | 2077396..2078055 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| NPX97_RS10230 (NPX97_10230) | 2078134..2078364 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| NPX97_RS10235 (NPX97_10235) | 2078477..2078851 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| NPX97_RS10240 (NPX97_10240) | 2078855..2079724 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| NPX97_RS10245 (NPX97_10245) | 2079741..2080079 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2080202..2080347 | - | 146 | - | - | Antitoxin |
| - | 2080238..2080340 | + | 103 | - | - | Toxin |
| NPX97_RS10250 (NPX97_10250) | 2080715..2080858 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| NPX97_RS10255 (NPX97_10255) | 2080963..2081931 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| NPX97_RS10260 (NPX97_10260) | 2082088..2082741 | + | 654 | WP_002911396.1 | protein-serine/threonine phosphatase | - |
| NPX97_RS10265 (NPX97_10265) | 2082738..2082929 | - | 192 | WP_002911395.1 | YebW family protein | - |
| NPX97_RS10270 (NPX97_10270) | 2083027..2083266 | - | 240 | WP_002911393.1 | YebV family protein | - |
| NPX97_RS10275 (NPX97_10275) | 2083382..2084815 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T264625 NZ_CP110967:2080238-2080340 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT264625 NZ_CP110967:c2080347-2080202 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
