264433

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 3844469..3845249 Replicon chromosome
Accession NZ_CP110886
Organism Dickeya solani strain DsR34

Toxin (Protein)


Gene name dhiT Uniprot ID A0A2K8W4P2
Locus tag OQ520_RS16720 Protein ID WP_022632927.1
Coordinates 3844469..3844726 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID A0A2K8W4X0
Locus tag OQ520_RS16725 Protein ID WP_022632928.1
Coordinates 3844734..3845249 (+) Length 172 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQ520_RS16710 (OQ520_07470) 3841229..3843379 - 2151 WP_022632925.1 formate dehydrogenase subunit alpha -
OQ520_RS16715 (OQ520_07475) 3843414..3843956 - 543 WP_022632926.1 4Fe-4S dicluster domain-containing protein -
OQ520_RS16720 (OQ520_07480) 3844469..3844726 + 258 WP_022632927.1 DUF4160 domain-containing protein Toxin
OQ520_RS16725 (OQ520_07485) 3844734..3845249 + 516 WP_022632928.1 DUF2442 domain-containing protein Antitoxin
OQ520_RS16730 (OQ520_07490) 3845328..3845825 - 498 WP_022632929.1 hydrogenase maturation peptidase HycI -
OQ520_RS16735 (OQ520_07495) 3845818..3846216 - 399 WP_022632930.1 formate hydrogenlyase maturation HycH family protein -
OQ520_RS16740 (OQ520_07500) 3846213..3847004 - 792 WP_022632931.1 NADH-quinone oxidoreductase subunit B family protein -
OQ520_RS16745 (OQ520_07505) 3847001..3847570 - 570 WP_022632932.1 hydrogenase 4 subunit H -
OQ520_RS16750 (OQ520_07510) 3847581..3849308 - 1728 WP_022632933.1 hydrogenase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-74)

Antitoxin

Uncharacterized protein HI1420

(80-157)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10007.56 Da        Isoelectric Point: 8.1243

>T264433 WP_022632927.1 NZ_CP110886:3844469-3844726 [Dickeya solani]
MPEVDRLAGLIFHLYFYDDERHYLPHVHVCYGNHELIISIRTGTEIEGYLPNNKRKMALAHIRAHREQLLSMWERAVVGR
NPGKL

Download         Length: 258 bp

Antitoxin


Download         Length: 172 a.a.        Molecular weight: 19099.82 Da        Isoelectric Point: 5.2747

>AT264433 WP_022632928.1 NZ_CP110886:3844734-3845249 [Dickeya solani]
MHKIVEVDVIGDFSLRLTYDDGLVCDINLYQYASSPVFSDVSLFIKFGLLPDGALEWLPDIKISASELRKKGEYVSHTLA
VRERHFADVISRAFYDAVIENRPEILQAALKIAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTHVSLATVVSLAHTVLQLE
ELQLEDLQLEE

Download         Length: 516 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8W4P2

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8W4X0

References