Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2814068..2814213 Replicon chromosome
Accession NZ_CP110873
Organism Enterobacter kobei strain SCLZS19

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2814075..2814178 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2814068..2814213 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQE50_RS13710 2809225..2809443 + 219 WP_006176198.1 hypothetical protein -
OQE50_RS13715 2809440..2809736 + 297 WP_042889503.1 DUF4406 domain-containing protein -
OQE50_RS13720 2809733..2809924 + 192 WP_266071098.1 DUF1382 family protein -
OQE50_RS13725 2810016..2810525 + 510 WP_252067359.1 HNH endonuclease -
OQE50_RS13730 2810528..2810743 + 216 WP_266071102.1 TraR/DksA family transcriptional regulator -
OQE50_RS13735 2810743..2811198 + 456 WP_139964092.1 hypothetical protein -
OQE50_RS13740 2811221..2811760 + 540 WP_266071106.1 HNH endonuclease -
OQE50_RS13745 2811870..2812511 + 642 WP_163358434.1 hypothetical protein -
OQE50_RS13750 2812671..2812943 + 273 WP_103142239.1 excisionase -
OQE50_RS13755 2812912..2813997 + 1086 WP_103142238.1 phage integrase Arm DNA-binding domain-containing protein -
- 2814068..2814213 + 146 - - Antitoxin
- 2814075..2814178 - 104 - - Toxin
OQE50_RS13760 2814317..2814655 - 339 WP_071922110.1 YebY family protein -
OQE50_RS13765 2814672..2815541 - 870 WP_023330712.1 copper homeostasis membrane protein CopD -
OQE50_RS13770 2815543..2815914 - 372 WP_014884301.1 CopC domain-containing protein YobA -
OQE50_RS13775 2816052..2816282 + 231 WP_013096102.1 DNA polymerase III subunit theta -
OQE50_RS13780 2816393..2817043 + 651 WP_193970475.1 carbon-nitrogen hydrolase family protein -
OQE50_RS13785 2817068..2817730 + 663 WP_014884303.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2754970..2835763 80793
- inside Prophage - - 2747420..2835763 88343


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T264417 NZ_CP110873:c2814178-2814075 [Enterobacter kobei]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT264417 NZ_CP110873:2814068-2814213 [Enterobacter kobei]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References