Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipB(antitoxin)
Location 3972579..3973029 Replicon chromosome
Accession NZ_CP110791
Organism Yersinia sp. SCPM-O-B-9106 (C-191)

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag OP863_RS17955 Protein ID WP_261369802.1
Coordinates 3972895..3973029 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag OP863_RS17950 Protein ID WP_186368366.1
Coordinates 3972579..3972893 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP863_RS17935 (OP863_17935) 3967997..3969646 - 1650 WP_038638574.1 Na+/H+ antiporter -
OP863_RS17940 (OP863_17940) 3969859..3971226 - 1368 WP_038638571.1 NCS2 family permease -
OP863_RS17945 (OP863_17945) 3971645..3972316 - 672 WP_145588503.1 glutathione S-transferase -
OP863_RS17950 (OP863_17950) 3972579..3972893 + 315 WP_186368366.1 helix-turn-helix transcriptional regulator Antitoxin
OP863_RS17955 (OP863_17955) 3972895..3973029 + 135 WP_261369802.1 hypothetical protein Toxin
OP863_RS17960 (OP863_17960) 3973132..3973449 + 318 WP_265525678.1 hypothetical protein -
OP863_RS17965 (OP863_17965) 3973514..3974062 - 549 WP_145588509.1 single-stranded DNA-binding protein -
OP863_RS17970 (OP863_17970) 3974475..3977306 + 2832 WP_038638557.1 excinuclease ABC subunit UvrA -
OP863_RS17975 (OP863_17975) 3977366..3977719 - 354 WP_038638554.1 MmcQ/YjbR family DNA-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(8-44)

Antitoxin

Cro/C1-type helix-turn-helix domain

(18-66)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 5368.06 Da        Isoelectric Point: 10.4251

>T264265 WP_261369802.1 NZ_CP110791:3972895-3973029 [Yersinia sp. SCPM-O-B-9106 (C-191)]
MTRRTQRLNIWMNGQRVGYWEKKRGEESLSYAQEWLANEQGRPL

Download         Length: 135 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11566.42 Da        Isoelectric Point: 10.3196

>AT264265 WP_186368366.1 NZ_CP110791:3972579-3972893 [Yersinia sp. SCPM-O-B-9106 (C-191)]
MDYPIKILSQLRPTLIGFRKNKGLTQASLAQLLGITQQSYAKLEANPASASVERLFKILHLLDIELILGEKKNASSHPSK
THPSEKSPAINLPSKHLPSKQEDW

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References