Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /COG5642-COG5654 |
| Location | 2278634..2279624 | Replicon | chromosome |
| Accession | NZ_CP110791 | ||
| Organism | Yersinia sp. SCPM-O-B-9106 (C-191) | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A386HEZ3 |
| Locus tag | OP863_RS10425 | Protein ID | WP_038632724.1 |
| Coordinates | 2279166..2279624 (+) | Length | 153 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A386HEX0 |
| Locus tag | OP863_RS10420 | Protein ID | WP_038632726.1 |
| Coordinates | 2278634..2279080 (+) | Length | 149 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OP863_RS10400 (OP863_10400) | 2274262..2274969 | + | 708 | WP_145588951.1 | murein tripeptide amidase MpaA | - |
| OP863_RS10405 (OP863_10405) | 2274966..2275937 | - | 972 | WP_265525232.1 | L-Ala-D/L-Glu epimerase | - |
| OP863_RS10410 (OP863_10410) | 2276089..2276592 | + | 504 | WP_038632730.1 | thiol peroxidase | - |
| OP863_RS10415 (OP863_10415) | 2276737..2278314 | - | 1578 | WP_145588948.1 | transcriptional regulator TyrR | - |
| OP863_RS10420 (OP863_10420) | 2278634..2279080 | + | 447 | WP_038632726.1 | type II toxin-antitoxin system antitoxin Xre | Antitoxin |
| OP863_RS10425 (OP863_10425) | 2279166..2279624 | + | 459 | WP_038632724.1 | RES family NAD+ phosphorylase | Toxin |
| OP863_RS10430 (OP863_10430) | 2279631..2280692 | - | 1062 | WP_038632723.1 | YcjF family protein | - |
| OP863_RS10435 (OP863_10435) | 2280689..2282086 | - | 1398 | WP_265525233.1 | YcjX family protein | - |
| OP863_RS10440 (OP863_10440) | 2282067..2282306 | - | 240 | WP_038632715.1 | phage shock protein PspD | - |
| OP863_RS10445 (OP863_10445) | 2282352..2282702 | - | 351 | WP_265526258.1 | envelope stress response membrane protein PspC | - |
| OP863_RS10450 (OP863_10450) | 2282756..2282983 | - | 228 | WP_038632713.1 | envelope stress response membrane protein PspB | - |
| OP863_RS10455 (OP863_10455) | 2283088..2283753 | - | 666 | WP_050291690.1 | phage shock protein PspA | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 153 a.a. Molecular weight: 17292.75 Da Isoelectric Point: 5.1666
>T264256 WP_038632724.1 NZ_CP110791:2279166-2279624 [Yersinia sp. SCPM-O-B-9106 (C-191)]
MKFYRIVMRRYLASTWTGYGAEIYGGRWNHKGHAAIYLASSVSLAMLETLVHIQDSSTLSEFELFQIEIEDSHILLLQPQ
DWPADWRSDPAPATTMDIGTEWLELESSLALLVPSTLVPSENNLLLNPRHKDFQACLNSVKPLSFAFDPRLK
MKFYRIVMRRYLASTWTGYGAEIYGGRWNHKGHAAIYLASSVSLAMLETLVHIQDSSTLSEFELFQIEIEDSHILLLQPQ
DWPADWRSDPAPATTMDIGTEWLELESSLALLVPSTLVPSENNLLLNPRHKDFQACLNSVKPLSFAFDPRLK
Download Length: 459 bp
Antitoxin
Download Length: 149 a.a. Molecular weight: 16177.61 Da Isoelectric Point: 9.1260
>AT264256 WP_038632726.1 NZ_CP110791:2278634-2279080 [Yersinia sp. SCPM-O-B-9106 (C-191)]
MRAYHPTPATKTGALWREIGLPASRGTVLVDSIKMGFSVDVIDGIHLWASIPKAEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDKGKAIAWMSTPIKGLGHRSPDSLLETETGALEVCDLIGRLEHGVFS
MRAYHPTPATKTGALWREIGLPASRGTVLVDSIKMGFSVDVIDGIHLWASIPKAEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDKGKAIAWMSTPIKGLGHRSPDSLLETETGALEVCDLIGRLEHGVFS
Download Length: 447 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|