Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1265218..1265753 Replicon chromosome
Accession NZ_CP110791
Organism Yersinia sp. SCPM-O-B-9106 (C-191)

Toxin (Protein)


Gene name relE Uniprot ID A0A386HCD1
Locus tag OP863_RS05735 Protein ID WP_038635036.1
Coordinates 1265466..1265753 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A386HCJ9
Locus tag OP863_RS05730 Protein ID WP_038635039.1
Coordinates 1265218..1265469 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP863_RS05705 (OP863_05705) 1260689..1261192 + 504 WP_265525972.1 ferredoxin-type protein NapF -
OP863_RS05710 (OP863_05710) 1261182..1261448 + 267 WP_019081761.1 chaperone NapD -
OP863_RS05715 (OP863_05715) 1261445..1263940 + 2496 WP_038635047.1 nitrate reductase catalytic subunit NapA -
OP863_RS05720 (OP863_05720) 1263975..1264442 + 468 WP_038635044.1 nitrate reductase cytochrome c-type subunit -
OP863_RS05725 (OP863_05725) 1264470..1265069 + 600 WP_145588881.1 cytochrome c-type protein NapC -
OP863_RS05730 (OP863_05730) 1265218..1265469 + 252 WP_038635039.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OP863_RS05735 (OP863_05735) 1265466..1265753 + 288 WP_038635036.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OP863_RS05740 (OP863_05740) 1265782..1266357 + 576 WP_038635033.1 GDP-mannose pyrophosphatase NudK -
OP863_RS05745 (OP863_05745) 1266601..1268880 + 2280 WP_038635031.1 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase -
OP863_RS05750 (OP863_05750) 1269031..1269504 - 474 WP_038635028.1 YaiI/YqxD family protein -
OP863_RS05755 (OP863_05755) 1269504..1270430 - 927 WP_265525973.1 oxygen-dependent coproporphyrinogen oxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11215.24 Da        Isoelectric Point: 10.3200

>T264255 WP_038635036.1 NZ_CP110791:1265466-1265753 [Yersinia sp. SCPM-O-B-9106 (C-191)]
MIYTVKFREEALKEWHKLDKTIQQQFAKKLKKCSDNPHIESAKLRGMKDCYKIKLRSSGFRLVYEVIDDILIVAVVAVGK
RERSEVYKLASERLR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9191.43 Da        Isoelectric Point: 4.1947

>AT264255 WP_038635039.1 NZ_CP110791:1265218-1265469 [Yersinia sp. SCPM-O-B-9106 (C-191)]
MPSVILSDTSASVSELKKNPMATVNAGAGFPVAILNRNQPAFYCVPAELYEQIMEALDDNELAKLVNERRNQPLHDIDLE
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References